Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 8/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8600205 | 0.85 | POLB (0.40) | POLBMEN1KMT2A | |
| SCHEMBL10543158 | 0.85 | POLB (0.40) | POLBMEN1KMT2A | |
| SCHEMBL10596773 | 0.80 | SMN1; SMN2 (0.33) | POLBTP53SMN1; SMN2 | |
| SCHEMBL10402624 | 0.80 | POLB (0.36) | POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL28473803 | 0.79 | MAPT (0.43) | POLBTP53SMN1; SMN2MEN1KMT2A | |
| SCHEMBL28435235 | 0.79 | MAPT (0.43) | POLBTP53SMN1; SMN2MEN1KMT2A | |
| SCHEMBL10401841 | 0.79 | HDAC1 (0.41) | POLBTP53MEN1KMT2A | |
| SCHEMBL10377087 | 0.77 | SMN1; SMN2 (0.34) | POLBSMN1; SMN2 | |
| SCHEMBL8597022 | 0.77 | ATM (0.42) | POLBMEN1KMT2A | |
| SCHEMBL7828421 | 0.77 | ATM (0.42) | POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0114750-A2 | Beta-lactam antibacterial agents | BEECHAM GROUP PLC (GB) | 1984-08-01 | — | — | EP | disclosed |