Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.32 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.32 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11181658 | 0.90 | POLB (0.35) | POLBSMN1; SMN2GAAHDAC1HDAC2 | |
| SCHEMBL10543158 | 0.82 | POLB (0.40) | POLBGAALMNAMAPTPDE3A | |
| SCHEMBL8600205 | 0.82 | POLB (0.40) | POLBGAALMNAMAPTPDE3A | |
| SCHEMBL10545818 | 0.82 | LMNA (0.35) | POLBSMN1; SMN2GAAHDAC1HDAC2 | |
| SCHEMBL11404138 | 0.80 | MAPT (0.37) | LMNAMAPTPDE3ASLC22A6SLC22A8 | |
| SCHEMBL11093687 | 0.80 | MC4R (0.37) | POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL28435235 | 0.79 | MAPT (0.43) | POLBSMN1; SMN2GAAHDAC1HDAC2 | |
| SCHEMBL28473803 | 0.79 | MAPT (0.43) | POLBSMN1; SMN2GAAHDAC1HDAC2 | |
| SCHEMBL10401841 | 0.79 | HDAC1 (0.41) | POLBGAAHDAC1HDAC2L3MBTL1 | |
| SCHEMBL10530994 | 0.76 | PDE3A (0.38) | POLBSMN1; SMN2GAAL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4940702-A | Cephem compounds | BEECHAM GROUP P.L.C. (GB) | 1990-07-10 | — | — | US | disclosed |
| EP-0211656-A2 | Cephalosporin derivatives, process for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1987-02-25 | — | — | EP | disclosed |