Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | RAB9A | P51151 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | GLA | P06280 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.47 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | MMP14 | P50281 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27791326 | 0.78 | KMT2A (0.55) | KDM4EKMT2ARAB9AALDH1A1HPGD | |
| SCHEMBL9415823 | 0.78 | KDM4E (0.58) | KDM4EKMT2ARAB9AALDH1A1HPGD | |
| SCHEMBL343177 | 0.78 | CA12 (0.61) | KDM4EKMT2ARAB9AALDH1A1HPGD | |
| SCHEMBL6679710 | 0.75 | ALDH1A1 (0.55) | KDM4EKMT2ARAB9AALDH1A1HPGD | |
| SCHEMBL5592991 | 0.75 | KMT2A (0.59) | KDM4EKMT2ARAB9AALDH1A1HPGD | |
| SCHEMBL27860753 | 0.74 | KMT2A (0.50) | KDM4EKMT2ARAB9AALDH1A1HPGD | |
| SCHEMBL9295692 | 0.74 | PARP1 (0.47) | KDM4EKMT2ARAB9AALDH1A1HPGD | |
| SCHEMBL4939236 | 0.73 | ALDH1A1 (0.61) | KDM4EKMT2ARAB9AALDH1A1HPGD | |
| Acridine SCHEMBL2261516 | 0.73 | ALDH1A1 (0.71) | KDM4EKMT2ARAB9AALDH1A1HPGD | |
| Acridine SCHEMBL3893642 | 0.73 | ALDH1A1 (0.71) | KDM4EKMT2ARAB9AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4479000-A | ANTITUMOR AGENTS | DEVELOPMENT FINANCE CORPORATION OF NEW ZEALAND (NZ) | 1984-10-23 | — | — | US | disclosed |