Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20261932 | 0.76 | MAOA (0.50) | HPGDMAOAMAOBALDH1A1KDM4E | |
| SCHEMBL11633686 | 0.74 | KDM4E (0.44) | HPGDHTTMAOAMAOBALDH1A1 | |
| SCHEMBL31238211 | 0.71 | MAOA (0.48) | HPGDHTTMAOAMAOBALDH1A1 | |
| SCHEMBL30129312 | 0.71 | HPGD (1.00) | HPGDHTTALDH1A1KDM4ENPC1 | |
| SCHEMBL18795836 | 0.70 | MAOA (0.58) | HPGDHTTMAOAMAOBALDH1A1 | |
| SCHEMBL13381758 | 0.69 | MAPT (0.49) | HTTALDH1A1KDM4EL3MBTL1NPC1 | |
| SCHEMBL6375232 | 0.69 | ALDH1A1 (0.49) | HPGDHTTMAOAMAOBALDH1A1 | |
| SCHEMBL6376517 | 0.69 | ALDH1A1 (0.50) | HPGDHTTMAOAMAOBALDH1A1 | |
| SCHEMBL2953050 | 0.68 | MAOA (0.46) | HPGDHTTMAOAMAOBALDH1A1 | |
| SCHEMBL7835598 | 0.68 | KDM4E (0.55) | HPGDMAOAMAOBALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4460403-A | 2,3-Dicyano 6 phenyl pyrazine herbicides | KYOWA GAS CHEMICAL INDUSTRY CO., LTD. (JP) | 1984-07-17 | — | — | US | disclosed |
| US-4259489-A | PREEMERGENCE AND POSTEMERGENCE HERBICIDES | KYOWA GAS CHEMICAL INDUSTRY CO. LTD. (JP) | 1981-03-31 | — | — | US | disclosed |