Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CCKBR | P32239 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | GSK3B | P49841 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11096194 | 0.90 | MEN1 (0.48) | KMT2AMEN1GAALMNASMN1; SMN2 | |
| SCHEMBL11093789 | 0.82 | CCKBR (0.48) | KMT2AMEN1GAALMNASMN1; SMN2 | |
| SCHEMBL11094189 | 0.80 | TSHR (0.50) | KMT2AMEN1SMN1; SMN2CCKBRTP53 | |
| SCHEMBL11166808 | 0.79 | BCHE (0.49) | KMT2AMEN1GAALMNASMN1; SMN2 | |
| SCHEMBL11092372 | 0.77 | CCKBR (0.47) | GAALMNASMN1; SMN2CCKBRTP53 | |
| SCHEMBL11088774 | 0.76 | TDP1 (0.47) | KMT2AMEN1GAALMNASMN1; SMN2 | |
| SCHEMBL11086091 | 0.76 | MAPT (0.55) | KMT2AGAALMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL11089059 | 0.76 | MAOA (0.43) | LMNASMN1; SMN2L3MBTL1TP53GSK3B | |
| SCHEMBL11088184 | 0.74 | GSK3B (0.39) | KMT2AMEN1GAALMNASMN1; SMN2 | |
| SCHEMBL11093300 | 0.72 | MAPT (0.51) | KMT2AMEN1GAALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0055917-B1 | NEW BENZOTHIAZINE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-11-21 | — | — | EP | disclosed |
| US-4397849-A | AUTOIMMUNE DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-08-09 | — | — | US | disclosed |
| EP-0055917-A1 | New benzothiazine derivatives, processes for preparation thereof and use thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1982-07-14 | — | — | EP | disclosed |