Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | GSK3B | P49841 | 2/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11096194 | 0.83 | MEN1 (0.48) | BCHEMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL11086091 | 0.82 | MAPT (0.55) | MAPTKMT2AALDH1A1NPC1KDM4E | |
| SCHEMBL11095086 | 0.79 | KMT2A (0.47) | MAPTMEN1KMT2AALDH1A1GSK3B | |
| SCHEMBL11092372 | 0.78 | CCKBR (0.47) | MAPTALDH1A1GSK3BNPC1RAB9A | |
| SCHEMBL11088774 | 0.77 | TDP1 (0.47) | MEN1KMT2AALDH1A1GSK3BNPC1 | |
| SCHEMBL11089059 | 0.77 | MAOA (0.43) | MAPTALDH1A1GSK3BNPC1RAB9A | |
| SCHEMBL11093789 | 0.76 | CCKBR (0.48) | MAPTMEN1KMT2AGSK3BNPC1 | |
| SCHEMBL11088184 | 0.75 | GSK3B (0.39) | MAPTMEN1KMT2AALDH1A1GSK3B | |
| SCHEMBL11094189 | 0.74 | TSHR (0.50) | MAPTMEN1KMT2ARAB9AKDM4E | |
| SCHEMBL11089030 | 0.73 | KDM4E (0.55) | BCHEMEN1KMT2AGSK3BKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4397849-A | AUTOIMMUNE DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-08-09 | — | — | US | disclosed |