Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | GSK3B | P49841 | 6/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.40 |
| ▸ | RELA | Q04206 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11096194 | 0.83 | MEN1 (0.48) | ALDH1A1SMN1; SMN2GSK3BMAPTL3MBTL1 | |
| SCHEMBL28629788 | 0.80 | GSK3B (0.62) | GSK3B | |
| SCHEMBL11089030 | 0.80 | KDM4E (0.55) | GSK3BKDM4EHSD17B10PKMTSHR | |
| SCHEMBL11166808 | 0.77 | BCHE (0.49) | ALDH1A1SMN1; SMN2GSK3BRAB9AMAPT | |
| SCHEMBL10675503 | 0.76 | MAOA (0.48) | MAOAALDH1A1SMN1; SMN2GSK3BRAB9A | |
| SCHEMBL11095086 | 0.76 | KMT2A (0.47) | ALDH1A1SMN1; SMN2GSK3BRAB9AMAPT | |
| SCHEMBL9830752 | 0.75 | MAOA (0.44) | MAOAALDH1A1SMN1; SMN2GSK3BRAB9A | |
| SCHEMBL20987671 | 0.75 | GSK3B (0.46) | SMN1; SMN2GSK3BL3MBTL1MAPK1CYP2C19 | |
| SCHEMBL11092372 | 0.75 | CCKBR (0.47) | ALDH1A1SMN1; SMN2GSK3BRAB9AMAPT | |
| SCHEMBL7289212 | 0.75 | MAOA (0.47) | MAOAALDH1A1SMN1; SMN2GSK3BRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0055917-B1 | NEW BENZOTHIAZINE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-11-21 | — | — | EP | disclosed |
| EP-0055917-A1 | New benzothiazine derivatives, processes for preparation thereof and use thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1982-07-14 | — | — | EP | disclosed |