Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CETP | P11597 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | UBE2N | P61088 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24017046 | 1.00 | OPRM1 (0.50) | OPRM1ALDH1A1TDP1DNM1CYP2D6 | |
| SCHEMBL9794616 | 0.94 | OPRM1 (0.46) | OPRM1ALDH1A1TDP1DNM1CYP2D6 | |
| SCHEMBL14232499 | 0.94 | OPRM1 (0.60) | OPRM1ALDH1A1TDP1DNM1CYP2D6 | |
| SCHEMBL8075374 | 0.91 | OPRM1 (0.57) | OPRM1DNM1CYP2D6SPHK1LMNA | |
| SCHEMBL5050619 | 0.91 | ALDH1A1 (0.46) | OPRM1ALDH1A1TDP1DNM1CYP2D6 | |
| SCHEMBL615266 | 0.90 | OPRM1 (0.63) | OPRM1DNM1CYP2D6SPHK1LMNA | |
| SCHEMBL8992571 | 0.88 | ALDH1A1 (0.50) | OPRM1ALDH1A1TDP1DNM1CYP2D6 | |
| SCHEMBL24017118 | 0.87 | OPRM1 (0.60) | OPRM1DNM1CYP2D6SPHK1LMNA | |
| SCHEMBL16432729 | 0.87 | OPRM1 (0.60) | OPRM1DNM1CYP2D6SPHK1LMNA | |
| SCHEMBL8934995 | 0.87 | OPRM1 (0.60) | OPRM1DNM1CYP2D6SPHK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116209525-A | Method for flotation of silicate-containing iron ore | 巴斯夫欧洲公司 | 2023-06-02 | — | — | CN | disclosed |
| WO-2021223156-A1 | DIBORON GLYCOL ESTER, PREPARATION METHOD THEREFOR, INTERMEDIATE THEREOF, AND APPLICATION THEREOF | 中国科学院上海有机化学研究所 | 2021-11-11 | — | — | WO | disclosed |
| US-10038148-B2 | Borylated compounds | THE UNIVERSITY OF MANCHESTER (GB) | 2018-07-31 | — | — | US | disclosed |
| US-20170110660-A1 | BORYLATED COMPOUNDS | THE UNIVERSITY OF MANCHESTER (GB) | 2017-04-20 | — | — | US | disclosed |
| CN-102850471-A | Use of catalysts for the metathesis degradation of nitrile rubber | LANXESS DEUTSCHLAND GMBH | 2013-01-02 | — | — | CN | disclosed |
| EP-0036129-B1 | PROCESS FOR THE PREPARATION OF IMIDAZOLES | BASF Aktiengesellschaft (DE) | 1984-06-13 | — | — | EP | disclosed |
| EP-0036521-B1 | PREPARATION OF 2-IMIDAZOLINES | BASF Aktiengesellschaft (DE) | 1983-10-19 | — | — | EP | disclosed |
| EP-0025191-B1 | PROCESS FOR THE PREPARATION OF IMIDAZOLES | BASF Aktiengesellschaft (DE) | 1983-05-25 | — | — | EP | disclosed |
| EP-0036519-B1 | PROCESS FOR THE PREPARATION OF IMIDAZOLE | BASF Aktiengesellschaft (DE) | 1983-03-02 | — | — | EP | disclosed |
| US-4340745-A | Preparation of 2-imidazolines | BASF AKTIENGESELLSCHAFT (DE) | 1982-07-20 | — | — | US | disclosed |
| US-4340744-A | METAL OXIDES AS CATALYSTS | BASF AKTIENGESELLSCHAFT (DE) | 1982-07-20 | — | — | US | disclosed |
| EP-0036521-A1 | Preparation of 2-imidazolines | BASF Aktiengesellschaft (DE) | 1981-09-30 | — | — | EP | disclosed |
| EP-0036519-A1 | Process for the preparation of imidazole | BASF Aktiengesellschaft (DE) | 1981-09-30 | — | — | EP | disclosed |
| EP-0036129-A1 | Process for the preparation of imidazoles | BASF Aktiengesellschaft (DE) | 1981-09-23 | — | — | EP | disclosed |
| EP-0025191-A1 | Process for the preparation of imidazoles | BASF Aktiengesellschaft (DE) | 1981-03-18 | — | — | EP | disclosed |
| US-4218559-A | FUSED PYRAZINE COMPOUNDS | AMERICAN CYANAMID COMPANY (US) | 1980-08-19 | — | — | US | disclosed |
| EP-0000208-B1 | PROCESS FOR THE PREPARATION OF IMIDAZOLES | BASF Aktiengesellschaft (DE) | 1980-04-30 | — | — | EP | disclosed |
| EP-0000208-A1 | Process for the preparation of imidazoles | BASF Aktiengesellschaft (DE) | 1979-01-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10038148-B2 | Borylated compounds | EYA3, EYA2, BLM | OPRM1 3211/4885ALDH1A1 1615/4885TDP1 1792/4885 |
| US-20170110660-A1 | BORYLATED COMPOUNDS | EYA3, EYA2, BLM | OPRM1 3211/4885ALDH1A1 1615/4885TDP1 1792/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.