Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 5/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11100115 | 0.88 | TSHR (0.45) | HTR4TSHRMEN1ALDH1A1KMT2A | |
| SCHEMBL11100788 | 0.86 | TSHR (0.43) | HTR4TSHRMEN1ALDH1A1KMT2A | |
| SCHEMBL11278608 | 0.85 | HTR4 (0.48) | HTR4TSHR | |
| SCHEMBL11095690 | 0.85 | KMT2A (0.51) | MEN1ALDH1A1KMT2A | |
| SCHEMBL11098785 | 0.85 | CHEK1 (0.41) | HTR4TSHRMEN1ALDH1A1KMT2A | |
| SCHEMBL11096503 | 0.83 | DRD2 (0.52) | HTR4CYP2D6CYP2C9ACHE | |
| SCHEMBL11094874 | 0.82 | DRD2 (0.61) | CYP2D6CYP2C9ACHE | |
| SCHEMBL11099827 | 0.82 | TSHR (0.49) | HTR4TSHRACHE | |
| SCHEMBL11092428 | 0.82 | DRD2 (0.52) | HTR4TSHR | |
| SCHEMBL11097949 | 0.81 | DRD2 (0.51) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0031219-B1 | ANILINE DERIVATIVES | BEECHAM GROUP PLC (GB) | 1984-03-07 | — | — | EP | disclosed |
| US-4350691-A | ANTIEMETICS | BEECHAM GROUP LIMITED (GB) | 1982-09-21 | — | — | US | disclosed |
| EP-0031219-A1 | Aniline derivatives | BEECHAM GROUP PLC (GB) | 1981-07-01 | — | — | EP | disclosed |