Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11095484 | 0.85 | HTR4 (0.52) | KMT2AALDH1A1MEN1 | |
| SCHEMBL11098580 | 0.85 | MAPT (0.51) | KMT2AALDH1A1MAPTGAAMEN1 | |
| SCHEMBL11100115 | 0.85 | TSHR (0.45) | KMT2AALDH1A1TMEM97SIGMAR1MEN1 | |
| SCHEMBL11100992 | 0.84 | ALDH1A1 (0.52) | KMT2AALDH1A1SIGMAR1MAPTGAA | |
| SCHEMBL11346054 | 0.83 | MAPK1 (0.60) | KMT2AALDH1A1MAPTMEN1 | |
| SCHEMBL11100788 | 0.83 | TSHR (0.43) | KMT2AALDH1A1TMEM97SIGMAR1MEN1 | |
| SCHEMBL11098785 | 0.82 | CHEK1 (0.41) | KMT2AALDH1A1TMEM97SIGMAR1MEN1 | |
| SCHEMBL11096830 | 0.82 | SMN1; SMN2 (0.54) | KMT2AALDH1A1MAPTMEN1 | |
| SCHEMBL11089660 | 0.81 | HCRTR1 (0.53) | KMT2AALDH1A1SIGMAR1MAPTMEN1 | |
| SCHEMBL11098498 | 0.81 | SIGMAR1 (0.54) | KMT2AALDH1A1SIGMAR1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0031219-B1 | ANILINE DERIVATIVES | BEECHAM GROUP PLC (GB) | 1984-03-07 | — | — | EP | disclosed |
| US-4350691-A | ANTIEMETICS | BEECHAM GROUP LIMITED (GB) | 1982-09-21 | — | — | US | disclosed |
| EP-0031219-A1 | Aniline derivatives | BEECHAM GROUP PLC (GB) | 1981-07-01 | — | — | EP | disclosed |