Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.42 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.40 |
| ▸ | FABP4 | P15090 | 1/20 | 0.40 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11094346 | 0.89 | CAMK2A (0.50) | CHRM1CXCL8PTGDR2CAMK2AFABP4 | |
| SCHEMBL11095644 | 0.84 | ALDH1A1 (0.41) | PPARATLR8HTR2ASLC6A4SLC6A2 | |
| SCHEMBL11094809 | 0.84 | CHRM1 (0.69) | CHRM1CXCL8SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL11095924 | 0.83 | CXCL8 (0.68) | CHRM1CXCL8SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL11090351 | 0.82 | CXCL8 (0.55) | CHRM1CXCL8TLR8SMN1; SMN2CAMK2A | |
| SCHEMBL872958 | 0.81 | CXCL8 (0.67) | CHRM1PPARACXCL8PTGDR2SLC1A5 | |
| SCHEMBL11121989 | 0.80 | CHRM1 (0.51) | CHRM1PPARACXCL8PTGDR2SLC1A5 | |
| SCHEMBL13905046 | 0.79 | HPGD (0.50) | CXCL8SMN1; SMN2MAPTMEN1KMT2A | |
| Ammonia Solution, Strong SCHEMBL872909 | 0.79 | CHRM1 (0.65) | CHRM1PPARACXCL8PTGDR2SLC1A5 | |
| SCHEMBL11096559 | 0.78 | HPGD (0.47) | CHRM1CXCL8SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4472433-A | Phenoxyphenyl acetic acids and their medicinal use | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-09-18 | — | — | US | disclosed |
| EP-0008226-B1 | PHENYL-ALKANOIC ACID DERIVATIVES, THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-11-02 | — | — | EP | disclosed |
| EP-0008226-A2 | Phenyl-alkanoic acid derivatives, the preparation thereof and pharmaceutical compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-02-20 | — | — | EP | disclosed |