Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | HSPB1 | P04792 | 2/20 | 0.48 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.47 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | EYA2 | O00167 | 1/20 | 0.44 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.44 |
| ▸ | ESRRA | P11474 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | MERTK | Q12866 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11093863 | 0.86 | KDM4E (0.50) | VCAM1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL11087204 | 0.86 | HSPB1 (0.66) | VCAM1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL5172391 | 0.86 | ALDH1A1 (0.66) | VCAM1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL11087491 | 0.86 | VCAM1 (0.57) | VCAM1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL6052442 | 0.86 | VCAM1 (0.53) | VCAM1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL11094289 | 0.83 | EPAS1 (0.51) | VCAM1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL6153036 | 0.83 | VCAM1 (0.47) | VCAM1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL11088781 | 0.83 | PLA2G7 (0.51) | VCAM1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL11093723 | 0.82 | VCAM1 (0.46) | VCAM1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL6296027 | 0.82 | VCAM1 (0.43) | VCAM1ALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4254144-A | Substituted benzonitriles having antiviral activity | THE DOW CHEMICAL COMPANY (US) | 1981-03-03 | — | — | US | claimed |
| EP-0034263-B1 | SUBSTITUTED BENZONITRILES AND COMPOSITIONS FOR INHIBITING VIRUSES | THE DOW CHEMICAL COMPANY (US) | 1984-09-26 | — | — | EP | disclosed |
| US-4332820-A | ESPECIALLY EFFECTIVE AGAINST PICORNOVIRUSES | THE DOW CHEMICAL COMPANY (US) | 1982-06-01 | — | — | US | disclosed |
| EP-0034263-A2 | Substituted benzonitriles and compositions for inhibiting viruses | THE DOW CHEMICAL COMPANY (US) | 1981-08-26 | — | — | EP | disclosed |
| US-4254144-A | Substituted benzonitriles having antiviral activity | THE DOW CHEMICAL COMPANY (US) | 1981-03-03 | — | — | US | disclosed |