SCHEMBL1109626

SCHEMBL1109626

O=C(c1c(Cl)cccc1Cl)P(C(=O)c1c(Cl)cccc1Cl)c1cccc2ccccc12

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 2/20 0.47
CYP1A2 P05177 1/20 0.47
ALDH1A1 P00352 2/20 0.41
TDP1 Q9NUW8 1/20 0.39
NR4A1 P22736 1/20 0.38
NR4A2 P43354 1/20 0.38
NR4A3 Q92570 1/20 0.38
CNR2 P34972 3/20 0.38
ABCG2 Q9UNQ0 1/20 0.38
KDM4E B2RXH2 3/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
LMNA P02545 1/20 0.37
MAPT P10636 1/20 0.37
HTT P42858 1/20 0.37
RORC P51449 1/20 0.37
RORB Q92753 1/20 0.37
CNR1 P21554 2/20 0.36
TRPV1 Q8NER1 1/20 0.35
MCL1 Q07820 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9515898 0.73 ALDH1A1 (0.48) CYP1A2ALDH1A1KDM4EKMT2AMAPT
SCHEMBL3415394 0.70 ABCG2 (0.37) CYP2A6CYP1A2ALDH1A1CNR2ABCG2
Acetone SCHEMBL28077026 0.69 CYP2A6 (0.74) CYP2A6CYP1A2ALDH1A1NR4A1NR4A2
SCHEMBL11897801 0.68 ALDH1A1 (0.47) ALDH1A1CNR1GAATSHR
SCHEMBL10529615 0.68 MEN1 (0.45) CYP1A2ALDH1A1MEN1KMT2ALMNA
SCHEMBL9120992 0.68 ALDH1A1 (0.39) ALDH1A1KDM4EMEN1KMT2ALMNA
SCHEMBL28181202 0.67 KMT2A (0.56) CYP2A6CYP1A2ALDH1A1TDP1KDM4E
SCHEMBL11751093 0.67 NPC1 (0.63) CYP1A2ALDH1A1KDM4EMEN1KMT2A
SCHEMBL517685 0.66 ALDH1A1 (0.53) CYP2A6CYP1A2ALDH1A1TDP1NR4A1
SCHEMBL29351228 0.66 CYP2A6 (1.00) CYP2A6CYP1A2ALDH1A1TDP1NR4A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2280032-B1 PHOTOPOLYMERIZABLE COMPOSITIONS TOKUYAMA DENTAL CORP (JP) 2015-01-07 EP disclosed
EP-2280032-A1 PHOTOPOLYMERIZABLE COMPOSITIONS Tokuyama Dental Corporation (JP) 2011-02-02 EP disclosed