SCHEMBL9120992

SCHEMBL9120992

Cc1ccc(C)c(P(C(=O)c2c(Cl)cccc2Cl)C(=O)c2c(Cl)cccc2Cl)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.39
GAA P10253 3/20 0.38
POLB P06746 1/20 0.38
MAPT P10636 1/20 0.37
PTGS2 P35354 2/20 0.36
RAB9A P51151 3/20 0.36
KMT2A Q03164 2/20 0.36
LMNA P02545 2/20 0.35
KDM4E B2RXH2 1/20 0.35
MEN1 O00255 1/20 0.35
TYK2 P29597 1/20 0.35
TAS1R3 Q7RTX0 1/20 0.35
TAS1R1 Q7RTX1 1/20 0.35
TAS1R2 Q8TE23 1/20 0.35
ABCB1 P08183 1/20 0.35
PBRM1 Q86U86 1/20 0.35
CHRNA7 P36544 1/20 0.34
FABP3 P05413 1/20 0.34
FABP4 P15090 1/20 0.34
PTGDR2 Q9Y5Y4 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3415394 0.82 ABCG2 (0.37) ALDH1A1GAAPOLBMAPTRAB9A
SCHEMBL22492932 0.79 CA12 (0.45) ALDH1A1GAAPOLBMAPTRAB9A
SCHEMBL3412204 0.75 HCRTR1 (0.41) ALDH1A1GAAPOLBMAPTRAB9A
SCHEMBL10870076 0.70 ALDH1A1 (0.40) ALDH1A1GAAPOLBMAPTPTGS2
SCHEMBL7177506 0.69 ALDH1A1 (0.39) ALDH1A1GAAPOLBMAPTPTGS2
Lithium SCHEMBL7177510 0.69 ALDH1A1 (0.39) ALDH1A1GAAPOLBMAPTPTGS2
SCHEMBL1109626 0.68 CYP2A6 (0.47) ALDH1A1GAAMAPTKMT2ALMNA
SCHEMBL58444 0.68 GAA (0.40) ALDH1A1GAAPOLBMAPTPTGS2
SCHEMBL22685704 0.68 ALDH1A1 (0.38) ALDH1A1GAAPOLBMAPTPTGS2
SCHEMBL11062242 0.68 GAA (0.40) ALDH1A1GAAPOLBMAPTPTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0325266-B1 DENTAL MATTER THERA Patent GmbH & Co. KG Gesellschaft für industrielle Schutzrechte (DE) 1993-08-11 EP claimed
WO-2023042743-A1 CURABLE HOT MELT ORGANOPOLYSILOXANE COMPOSITION, CURED PRODUCT THEREOF AND METHOD FOR PRODUCING FILM, ETC. COMPRISING SAME ダウ・東レ株式会社 2023-03-23 WO disclosed
WO-2023042744-A1 CURABLE ORGANOPOLYSILOXANE COMPOSITION, ORGANOPOLYSILOXANE ADHESIVE LAYER OBTAINED BY CURING SAME, AND LAMINATE ダウ・東レ株式会社 2023-03-23 WO disclosed
WO-2023042745-A1 CURABLE ORGANOPOLYSILOXANE COMPOSITION, SLIGHTLY-ADHESIVE ORGANOPOLYSILOXANE ADHESIVE AGENT LAYER OBTAINED BY CURING SAME, AND LAMINATE ダウ・東レ株式会社 2023-03-23 WO disclosed
WO-2023042913-A1 METHOD FOR PRODUCING DENTURE クラレノリタケデンタル株式会社 2023-03-23 WO disclosed
WO-2023017746-A1 CURABLE HOT MELT SILICONE COMPOSITION, CURED PRODUCT OF SAID COMPOSITION, AND METHOD FOR PRODUCING FILM OR THE LIKE COMPRISING SAID COMPOSITION ダウ・東レ株式会社 2023-02-16 WO disclosed
WO-2020130143-A1 DENTAL ADHESIVE COMPOSITION クラレノリタケデンタル株式会社 2020-06-25 WO disclosed
WO-2019203356-A1 ADHESIVE COMPOSITION FOR DENTAL USE クラレノリタケデンタル株式会社 2019-10-24 WO disclosed
WO-2019189219-A1 CURABLE RESIN COMPOSITION, DRY FILM, CURED PRODUCT, AND PRINTED WIRING BOARD 太陽インキ製造株式会社 2019-10-03 WO disclosed
WO-2019189220-A1 DRY FILM, CURED PRODUCT, AND PRINTED WIRING BOARD 太陽インキ製造株式会社 2019-10-03 WO disclosed
EP-3366269-A1 CURABLE COMPOSITION AND DENTAL FILLING RESTORATIVE MATERIAL Tokuyama Dental Corporation (JP) 2018-08-29 EP disclosed
EP-3053571-B1 Process for the preparation of a particulate dental filler composition DENTSPLY DETREY GMBH (DE) 2017-03-22 EP disclosed
EP-3053571-A1 Process for the preparation of a particulate dental filler composition Dentsply DeTrey GmbH (DE) 2016-08-10 EP disclosed
US-5472991-A Irradiating curable composition containing unsaturated monomer, fillers, two photoinitiators activated by light of different wavelengths, first at one wavelength, then another 501 ESPE STIFTUNG & CO. PRODUKTIONS-UND (DE) 1995-12-05 US disclosed
EP-0184095-B1 BISACYLPHOSPHINOXIDES, THEIR PREPARATION AND USE ESPE Stiftung & Co Produktions- und Vertriebs KG (DE) 1989-07-05 EP disclosed
US-4792632-A ADDITION POLYMER PHOTOINITIATORS ESPE FABRIK PHARMAZEUTISCHER PRAPARATE GMBH (DE) 1988-12-20 US disclosed
US-4737593-A PHOTOINITIATORS FOR ADDITION POLYMERIZATION; DENTISTRY Fabrik Pharmazeutischer Praparate (DE) 1988-04-12 US disclosed
EP-0184095-A2 Bisacylphosphinoxides, their preparation and use ESPE Stiftung & Co Produktions- und Vertriebs KG (DE) 1986-06-11 EP disclosed