Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | FEN1 | P39748 | 1/20 | 0.43 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | FABP3 | P05413 | 1/20 | 0.39 |
| ▸ | FABP4 | P15090 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | APAF1 | O14727 | 1/20 | 0.37 |
| ▸ | TDP2 | O95551 | 1/20 | 0.37 |
| ▸ | NSD2 | O96028 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | GALK1 | P51570 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10529615 | 0.89 | MEN1 (0.45) | ALDH1A1FEN1PBRM1FABP3FABP4 | |
| SCHEMBL11897801 | 0.86 | ALDH1A1 (0.47) | ALDH1A1FEN1TSHRAKR1B1CES2 | |
| SCHEMBL7114346 | 0.84 | ALDH1A1 (0.48) | ALDH1A1FEN1PBRM1TSHRAKR1B1 | |
| SCHEMBL27910820 | 0.82 | ALDH1A1 (0.47) | ALDH1A1FEN1PBRM1TSHRAKR1B1 | |
| SCHEMBL10526951 | 0.79 | TSHR (0.58) | ALDH1A1FEN1TSHRCES2CES1 | |
| SCHEMBL3420869 | 0.77 | ALDH1A1 (0.41) | ALDH1A1FEN1MAPTNPC1KDM4E | |
| SCHEMBL14365187 | 0.76 | L3MBTL1 (0.41) | ALDH1A1TSHRAKR1B1FABP3FABP4 | |
| SCHEMBL7601305 | 0.76 | CA12 (0.45) | TSHRFABP4RORC | |
| SCHEMBL10527004 | 0.76 | TAS1R3 (0.44) | MAPTNPC1KMT2ACYP1A2 | |
| SCHEMBL7182270 | 0.74 | PLK1 (0.47) | ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0325266-B1 | DENTAL MATTER | THERA Patent GmbH & Co. KG Gesellschaft für industrielle Schutzrechte (DE) | 1993-08-11 | — | — | EP | claimed |
| EP-0184095-B1 | BISACYLPHOSPHINOXIDES, THEIR PREPARATION AND USE | ESPE Stiftung & Co Produktions- und Vertriebs KG (DE) | 1989-07-05 | — | — | EP | claimed |