Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.46 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | PRCP | P42785 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3924761 | 0.97 | OPRM1 (0.48) | OPRM1OPRL1LMNATSHRKCNA3 | |
| SCHEMBL29101204 | 0.80 | OPRM1 (0.53) | OPRM1OPRL1LMNATSHRSLC6A4 | |
| SCHEMBL24946122 | 0.78 | SLC6A4 (0.57) | OPRM1OPRL1LMNATSHRSLC6A4 | |
| Hydrochloric Acid SCHEMBL6203736 | 0.77 | SLC6A4 (0.55) | OPRM1OPRL1LMNATSHRSLC6A4 | |
| Ethylene SCHEMBL11098322 | 0.76 | KCNA3 (0.43) | LMNATSHRKCNA3HDAC3HDAC1 | |
| Ethylene SCHEMBL11099442 | 0.76 | OPRM1 (0.58) | OPRM1OPRL1LMNATSHRKCNA3 | |
| SCHEMBL29101213 | 0.76 | OPRM1 (0.49) | OPRM1OPRL1LMNASLC6A4KMT2A | |
| Ethylene SCHEMBL11095151 | 0.73 | MEN1 (0.53) | OPRM1OPRL1KCNA3MEN1KMT2A | |
| Ethylene SCHEMBL11087552 | 0.73 | LMNA (0.38) | OPRM1OPRL1LMNATSHRKCNA3 | |
| SCHEMBL517361 | 0.72 | OPRM1 (0.61) | OPRM1OPRL1LMNATSHRKCNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4460604-A | ANALGESICS, NARCOTIC ANTAGONIST | THE UPJOHN COMPANY (US) | 1984-07-17 | — | — | US | disclosed |
| US-4180584-A | ANALGESIC; NARCOTIC ANTAGONIST | THE UPJOHN COMPANY (US) | 1979-12-25 | — | — | US | disclosed |
| US-4065573-A | ANALGESICS | THE UPJOHN COMPANY (US) | 1977-12-27 | — | — | US | disclosed |