Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 9/20 | 0.53 |
| ▸ | OPRL1 | P41146 | 9/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.53 |
| ▸ | KCNA3 | P22001 | 3/20 | 0.41 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL735724 | 0.96 | MEN1 (0.57) | MEN1CYP2C9KMT2AOPRM1OPRL1 | |
| Hydrochloric Acid SCHEMBL11093542 | 0.95 | MEN1 (0.55) | MEN1CYP2C9KMT2AOPRM1OPRL1 | |
| Ethylene SCHEMBL11096036 | 0.83 | SLC6A3 (0.42) | MEN1CYP2C9KMT2AOPRM1OPRL1 | |
| Ethylene SCHEMBL11093865 | 0.82 | HDAC4 (0.41) | MEN1CYP2C9KMT2AOPRM1OPRL1 | |
| Ethylene SCHEMBL11091724 | 0.81 | MMP2 (0.48) | OPRM1OPRL1 | |
| SCHEMBL1822928 | 0.80 | OPRM1 (0.74) | OPRM1OPRL1OPRK1OGFRL1 | |
| Ethylene SCHEMBL11096239 | 0.80 | OPRM1 (0.39) | MEN1CYP2C9KMT2AOPRM1OPRL1 | |
| SCHEMBL11097091 | 0.80 | SLC6A4 (0.39) | MEN1CYP2C9KMT2AOPRM1OPRL1 | |
| Ethylene SCHEMBL11079878 | 0.79 | HDAC3 (0.43) | MEN1KMT2AOPRM1OPRL1OPRK1 | |
| SCHEMBL11092884 | 0.79 | SLC6A4 (0.40) | MEN1CYP2C9KMT2AOPRM1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4460604-A | ANALGESICS, NARCOTIC ANTAGONIST | THE UPJOHN COMPANY (US) | 1984-07-17 | — | — | US | disclosed |
| US-4180584-A | ANALGESIC; NARCOTIC ANTAGONIST | THE UPJOHN COMPANY (US) | 1979-12-25 | — | — | US | disclosed |
| US-4065573-A | ANALGESICS | THE UPJOHN COMPANY (US) | 1977-12-27 | — | — | US | disclosed |