Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.54 |
| ▸ | OPRK1 | P41145 | 9/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 8/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11096355 | 0.82 | KCNH2 (0.59) | NR1H2OPRK1KCNH2OPRM1OPRD1 | |
| SCHEMBL7744542 | 0.82 | ALDH1A1 (0.53) | OPRK1KCNH2OPRM1L3MBTL1KMT2A | |
| Hydrochloric Acid SCHEMBL11094804 | 0.81 | KCNH2 (0.57) | NR1H2OPRK1KCNH2OPRM1OPRD1 | |
| Hydrochloric Acid SCHEMBL30028803 | 0.81 | ALDH1A1 (0.52) | OPRK1KCNH2OPRM1L3MBTL1KMT2A | |
| SCHEMBL11095893 | 0.80 | TSHR (0.44) | OPRK1KCNH2OPRM1 | |
| SCHEMBL8809184 | 0.79 | DRD2 (0.61) | — | |
| Hydrochloric Acid SCHEMBL9536536 | 0.78 | DRD2 (0.60) | — | |
| SCHEMBL9631914 | 0.77 | BCHE (0.54) | L3MBTL1 | |
| SCHEMBL8912103 | 0.77 | L3MBTL1 (0.56) | OPRK1L3MBTL1KMT2AUSP2 | |
| SCHEMBL15934617 | 0.76 | OPRK1 (0.48) | OPRK1KCNH2OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5561149-A | FOR NASAL ADMINISTRATION | SANDOZ LTD. (CH) | 1996-10-01 | — | — | US | disclosed |
| EP-0031219-B1 | ANILINE DERIVATIVES | BEECHAM GROUP PLC (GB) | 1984-03-07 | — | — | EP | disclosed |
| US-4350691-A | ANTIEMETICS | BEECHAM GROUP LIMITED (GB) | 1982-09-21 | — | — | US | disclosed |