Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11098411 | 0.96 | OPRM1 (0.42) | DRD3OPRM1SLC6A4OPRD1DRD2 | |
| SCHEMBL11093463 | 0.92 | DRD3 (0.39) | DRD3OPRM1OPRD1DRD2 | |
| SCHEMBL11068638 | 0.90 | OPRM1 (0.52) | DRD3OPRM1SLC6A4OPRD1OPRL1 | |
| SCHEMBL11088337 | 0.88 | SIGMAR1 (0.41) | OPRM1SLC6A4OPRD1OPRK1 | |
| Ethylene SCHEMBL10833583 | 0.88 | OPRM1 (0.50) | DRD3OPRM1SLC6A4OPRD1OPRL1 | |
| SCHEMBL11093314 | 0.86 | OPRM1 (0.48) | DRD3OPRM1SLC6A4OPRD1DRD2 | |
| SCHEMBL11094528 | 0.84 | OPRM1 (0.42) | DRD3OPRM1SLC6A4OPRD1OPRK1 | |
| Ethylene SCHEMBL11092451 | 0.84 | OPRM1 (0.46) | DRD3OPRM1SLC6A4OPRD1DRD2 | |
| SCHEMBL11096511 | 0.83 | OPRD1 (0.41) | OPRM1OPRD1OPRK1 | |
| Ethylene SCHEMBL11092467 | 0.82 | OPRM1 (0.40) | DRD3OPRM1SLC6A4OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4460604-A | ANALGESICS, NARCOTIC ANTAGONIST | THE UPJOHN COMPANY (US) | 1984-07-17 | — | — | US | disclosed |
| US-4180584-A | ANALGESIC; NARCOTIC ANTAGONIST | THE UPJOHN COMPANY (US) | 1979-12-25 | — | — | US | disclosed |
| US-4065573-A | ANALGESICS | THE UPJOHN COMPANY (US) | 1977-12-27 | — | — | US | disclosed |