Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.61 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.48 |
| ▸ | SCN1A | P35498 | 1/20 | 0.48 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.48 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11098400 | 0.89 | OPRM1 (0.53) | OPRM1ADRA1DADRA1AADRA1B | |
| SCHEMBL11097092 | 0.89 | OPRM1 (0.53) | OPRM1ADRA1DADRA1AADRA1B | |
| SCHEMBL11100662 | 0.89 | OPRM1 (0.53) | OPRM1ADRA1DADRA1AADRA1B | |
| SCHEMBL9943304 | 0.85 | DRD2 (0.61) | OPRM1 | |
| SCHEMBL11096216 | 0.85 | OPRM1 (0.57) | OPRM1 | |
| Hydrochloric Acid SCHEMBL11096032 | 0.84 | DRD2 (0.61) | OPRM1 | |
| SCHEMBL11098879 | 0.83 | OPRM1 (0.58) | OPRM1ADRA1DADRA1AADRA1B | |
| Axamozide SCHEMBL11022863 | 0.82 | OPRM1 (0.60) | OPRM1ADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL11100748 | 0.82 | OPRM1 (0.60) | OPRM1ADRA1DADRA1AADRA1B | |
| Axamozide SCHEMBL11027857 | 0.81 | OPRM1 (0.59) | OPRM1ADRA2AADRA2BADRA2CADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4470989-A | Neuroleptic n-oxacyclyl-alkylpiperidine derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-09-11 | — | — | US | disclosed |
| EP-0068261-A1 | N-oxacyclyl-alkylpiperidine derivatives, their preparation, pharmaceutical preparations containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-01-05 | — | — | EP | disclosed |