Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | LPO | P22079 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | SI | P14410 | 1/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.40 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29837126 | 0.98 | ALDH1A1 (0.42) | ALDH1A1LPOLMNACYP1A2HSD17B10 | |
| SCHEMBL27810242 | 0.98 | ALDH1A1 (0.42) | ALDH1A1LPOLMNACYP1A2HSD17B10 | |
| Pyridine SCHEMBL28155739 | 0.86 | KDM4E (0.40) | ALDH1A1LPOLMNACYP1A2HSD17B10 | |
| SCHEMBL23953095 | 0.84 | ALDH1A1 (0.44) | ALDH1A1LMNATSHRL3MBTL1GAA | |
| SCHEMBL28810272 | 0.79 | TSHR (0.49) | ALDH1A1LMNAHSD17B10TSHRL3MBTL1 | |
| SCHEMBL12989709 | 0.78 | — | — | |
| SCHEMBL28099494 | 0.78 | — | — | |
| SCHEMBL29266177 | 0.78 | LPO (0.42) | ALDH1A1LPOLMNACYP1A2TSHR | |
| SCHEMBL15853322 | 0.78 | NR1H2 (0.31) | — | |
| SCHEMBL9091102 | 0.78 | LMNA (0.38) | ALDH1A1LPOLMNACYP1A2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108299270-A | A kind of preparation method of disubstituted azole compounds | 中国科学院宁波材料技术与工程研究所 | 2018-07-20 | — | — | CN | claimed |
| CN-113748184-B | Boron-containing cyclic light-emitting compound and color conversion film containing same | 日东电工株式会社 | 2025-04-04 | — | — | CN | disclosed |
| CN-117794896-A | Protease inhibitors for the treatment of coronavirus infections | 斯克里普斯研究学院 | 2024-03-29 | — | — | CN | disclosed |
| CN-116396356-A | Functionalized polypeptide derivative as inhibiting virus main protease, preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2023-07-07 | — | — | CN | disclosed |
| CN-113748184-A | Boron-containing cyclic light-emitting compound and color conversion film containing the same | 日东电工株式会社 | 2021-12-03 | — | — | CN | disclosed |
| CN-112638376-A | Substituted tetrahydrocyclopenta [ c ] pyrroles, substituted dihydropyrrolizines, analogs thereof and methods of use thereof | 爱彼特生物制药公司 | 2021-04-09 | — | — | CN | disclosed |
| CN-110437206-A | Alternate foldamer of pyridine-pyrrole and preparation method thereof | UNIV SHANGHAI | 2019-11-12 | — | — | CN | disclosed |
| CN-106554301-B | A kind of preparation method of saxagliptin key intermediate | 深圳翰宇药业股份有限公司 | 2018-09-21 | — | — | CN | disclosed |
| CN-108299270-A | A kind of preparation method of disubstituted azole compounds | 中国科学院宁波材料技术与工程研究所 | 2018-07-20 | — | — | CN | disclosed |
| CN-105331960-B | Lug aluminium strip Surface treatment passivation solution | 麦垲门电子科技(上海)有限公司 | 2017-11-28 | — | — | CN | disclosed |
| WO-2000050470-A2 | CATALYSTS CONTAINING N-PYRROLYL SUBSTITUTED NITROGEN DONORS | EASTMAN CHEMICAL COMPANY (US) | 2000-08-31 | — | — | WO | disclosed |
| EP-0912548-A1 | PYRIDYLPYRROLE COMPOUNDS USEFUL AS INTERLEUKIN- AND TNF ANTAGONISTS | PFIZER INC. (US) | 1999-05-06 | — | — | EP | disclosed |
| WO-1998002430-A1 | PYRIDYLPYRROLE COMPOUNDS USEFUL AS INTERLEUKIN- AND TNF ANTAGONISTS | PFIZER PHARMACEUTICALS INC. (JP) | 1998-01-22 | — | — | WO | disclosed |
| US-5708168-A | FOR TREATING OR PREVENTING NEURONAL LOSS | STATE OF OREGON, ACTING BY AND THROUGH THE OREGON STATE BOARD OF HIGHER EDUCATION, ACTING FOR AND ON BEHALF OF THE OREGON HEALTH SCIENCES UNIVERSITY AND THE UNIVERSITY OF OREGON, EUGENE OREGON (US) | 1998-01-13 | — | — | US | disclosed |
| WO-1996015112-A1 | AZEPINE SYNTHESIS VIA A DIELS-ALDER REACTION | ACEA PHARMACEUTICALS, INC. (US) | 1996-05-23 | — | — | WO | disclosed |
| US-5476933-A | Condensation, ring expansion | STATE OF OREGON, ACTING BY AND THROUGH THE OREGON STATE BOARD OF HIGHER EDUCATION, ACTING FOR AND ON BEHALF OF THE OREGON HEALTH SCIENCES UNIVERSITY AND THE UNIVERSITY OF OREGON (US) | 1995-12-19 | — | — | US | disclosed |
| US-4584369-A | ANTICANCER AGENTS | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1986-04-22 | — | — | US | disclosed |
| EP-0071227-A1 | Anti-leukemic beta-glycosyl C-nucleosides | Sloan-Kettering Institute For Cancer Research (US) | 1983-02-09 | — | — | EP | disclosed |
| US-4070366-A | RING ALKYLATION OF SUBSTITUTED PYRROLES, ONE STEP | CANADIAN PATENTS & DEVELOPMENT LIMITED (US) | 1978-01-24 | — | — | US | disclosed |
| US-3980089-A | Novel heterocyclic flavoring compositions and processes | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1976-09-14 | — | — | US | disclosed |