Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | LPO | P22079 | 2/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1109685 | 0.78 | ALDH1A1 (0.43) | LMNALPOCYP1A2ALDH1A1TSHR | |
| SCHEMBL27810242 | 0.76 | ALDH1A1 (0.42) | LMNALPOCYP1A2ALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL29837126 | 0.76 | ALDH1A1 (0.42) | LMNALPOPIN1CYP1A2ALDH1A1 | |
| SCHEMBL425250 | 0.74 | ALDH1A1 (0.56) | LMNAPIN1ALDH1A1MEN1NPC1 | |
| SCHEMBL8906464 | 0.72 | PIN1 (0.39) | LMNALPOPIN1CYP1A2ALDH1A1 | |
| SCHEMBL10028356 | 0.72 | MAPT (0.40) | LMNAPIN1CYP1A2ALDH1A1MEN1 | |
| SCHEMBL27504170 | 0.72 | METAP2 (0.42) | ALDH1A1KDM4EPOLBRAB9A | |
| SCHEMBL3086153 | 0.71 | ALDH1A1 (0.53) | LMNAPIN1ALDH1A1MEN1NPC1 | |
| SCHEMBL1363735 | 0.70 | SOAT1 (0.48) | LMNAPIN1ALDH1A1MEN1NPC1 | |
| SCHEMBL21765608 | 0.70 | KDM4E (0.33) | LMNAPIN1ALDH1A1MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532381-A | Process for preparing pyrrolizine derivatives | DONG KOOK PHARMACEUTICAL CO., LTD. (KR) | 1996-07-02 | — | — | US | disclosed |