Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11038855 | 0.87 | TP53 (0.63) | SMN1; SMN2TP53POLBALDH1A1LMNA | |
| SCHEMBL11044738 | 0.86 | TP53 (0.49) | SMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL11095871 | 0.85 | TP53 (0.54) | SMN1; SMN2TP53KDM4EALDH1A1NPSR1 | |
| SCHEMBL11041232 | 0.82 | KMT2A (0.49) | SMN1; SMN2TP53KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL11040213 | 0.81 | IDO1 (0.43) | SMN1; SMN2TP53ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL11044671 | 0.80 | POLB (0.49) | SMN1; SMN2TP53POLBALDH1A1L3MBTL1 | |
| SCHEMBL11047507 | 0.79 | MAPT (0.43) | SMN1; SMN2TP53POLBALDH1A1CYP1A2 | |
| SCHEMBL10983009 | 0.78 | SMN1; SMN2 (0.76) | SMN1; SMN2TP53KDM4EPOLBALDH1A1 | |
| SCHEMBL22737578 | 0.76 | SMN1; SMN2 (0.62) | SMN1; SMN2TP53MAPK14KDM4EALDH1A1 | |
| SCHEMBL11042738 | 0.73 | SMN1; SMN2 (0.49) | SMN1; SMN2TP53KDM4EALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0073931-B1 | ANILINO-1,2,3-TRIAZOLE DERIVATIVES, MEDICAMENTS CONTAINING THEM, PROCESS FOR PREPARING THEM, AND THEIR USE | BOEHRINGER INGELHEIM KG (DE) | 1985-02-13 | — | — | EP | disclosed |
| EP-0073931-A1 | Anilino-1,2,3-triazole derivatives, medicaments containing them, process for preparing them, and their use | BOEHRINGER INGELHEIM KG (DE) | 1983-03-16 | — | — | EP | disclosed |