Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | FYN | P06241 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | CA6 | P23280 | 1/20 | 0.50 |
| ▸ | CDK2 | P24941 | 1/20 | 0.50 |
| ▸ | MMP12 | P39900 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL896864 | 0.83 | SELL (0.50) | ALDH1A1HPGDHSD17B10ALOX15RECQL | |
| SCHEMBL2552123 | 0.80 | ALDH1A1 (0.58) | ALDH1A1HPGDHSD17B10LMNACA1 | |
| SCHEMBL11568888 | 0.80 | ALDH1A1 (0.58) | ALDH1A1HPGDHSD17B10LMNACA1 | |
| SCHEMBL31451521 | 0.80 | ALDH1A1 (0.58) | ALDH1A1HPGDHSD17B10LMNACA1 | |
| SCHEMBL15553671 | 0.77 | TRPA1 (0.48) | ALDH1A1HPGDHSD17B10LMNACA1 | |
| SCHEMBL3559324 | 0.76 | ALDH1A1 (0.50) | ALDH1A1HPGDHSD17B10LMNACA1 | |
| SCHEMBL22529547 | 0.76 | ALDH1A1 (0.50) | ALDH1A1HPGDHSD17B10LMNACA1 | |
| SCHEMBL29552052 | 0.76 | KDM4E (0.67) | ALDH1A1HPGDHSD17B10LMNACA1 | |
| SCHEMBL424097 | 0.76 | KDM4E (0.67) | ALDH1A1HPGDHSD17B10LMNACA1 | |
| Ammonia Solution, Strong SCHEMBL8664317 | 0.74 | KDM4E (0.64) | ALDH1A1HPGDHSD17B10LMNACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250296953-A1 | 3,4-THIAZOLO-STEROIDS AND METHODS OF MAKING AND USING THE SAME | Arkansas State University - Jonesboro | 2025-09-25 | — | — | US | disclosed |
| US-12319713-B2 | 3,4-thiazolo-steroids and methods of making and using the same | Arkansas State University—Jonesboro (US) | 2025-06-03 | — | — | US | disclosed |
| US-20210317160-A1 | 3,4-THIAZOLO-STEROIDS AND METHODS OF MAKING AND USING THE SAME | Arkansas State University - Jonesboro | 2021-10-14 | — | — | US | disclosed |
| WO-2020018997-A1 | 3,4-THIAZOLO STEROIDS AND METHODS OF MAKING AND USING THE SAME | Arkansas State University - Jonesboro (US) | 2020-01-23 | — | — | WO | disclosed |
| EP-0033151-B1 | HYDROXYPHENYL-THIAZOLE-THIAZOLINE AND -THIAZOLIDINE CARBOXYLIC ACIDS, PROCESS FOR THEIR PREPARATION AND THESE COMPOUNDS FOR USE IN INFLUENCING THE COLLAGEN METABOLISM | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-05-02 | — | — | EP | disclosed |
| EP-0033151-A1 | Hydroxyphenyl-thiazole-thiazoline and -thiazolidine carboxylic acids, process for their preparation and these compounds for use in influencing the collagen metabolism | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-08-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12319713-B2 | 3,4-thiazolo-steroids and methods of making and using the same | HSD17B7, HSD17B3, NR3C2 | ALDH1A1 826/4885HPGD 403/4885HSD17B10 49/4885 |
| US-20210317160-A1 | 3,4-THIAZOLO-STEROIDS AND METHODS OF MAKING AND USING THE SAME | HSD17B7, HSD17B3, NR3C2 | ALDH1A1 826/4885HPGD 403/4885HSD17B10 49/4885 |
| US-20250296953-A1 | 3,4-THIAZOLO-STEROIDS AND METHODS OF MAKING AND USING THE SAME | HSD17B7, HSD17B3, NR3C2 | ALDH1A1 826/4885HPGD 403/4885HSD17B10 49/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.