Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 4/20 | 0.48 |
| ▸ | CA2 | P00918 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 2/20 | 0.45 |
| ▸ | CES1 | P23141 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8754771 | 0.85 | CYP2C9 (0.50) | LMNAALDH1A1MEN1KMT2APPARG | |
| SCHEMBL12264556 | 0.80 | LDHA (0.46) | LDHACA1CA2NPC1LMNA | |
| SCHEMBL726401 | 0.80 | LDHA (0.46) | LDHACA1CA2NPC1LMNA | |
| SCHEMBL10783459 | 0.80 | ALDH1A1 (0.53) | LMNASMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL1744968 | 0.79 | HTT (0.66) | LDHALMNARAB9AALDH1A1KMT2A | |
| SCHEMBL11003311 | 0.78 | CYP2C9 (0.44) | CA1CA2LMNAALDH1A1CES2 | |
| SCHEMBL6934273 | 0.78 | MAPT (0.55) | NPC1LMNARAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL74368 | 0.77 | LMNA (0.44) | LMNASMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL4552643 | 0.77 | LMNA (0.44) | LMNASMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL28622779 | 0.76 | MEN1 (0.46) | CA1CA2NPC1LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4461911-A | FROM THIOGLYCOLIC ACID AND AN ARYLDIAZONIUM SALT, COPPER SALT, ACID MEDIUM | BAYER AKTIENGESELLSCHAFT (DE) | 1984-07-24 | — | — | US | disclosed |