Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.44 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.43 |
| ▸ | WNT3A | P56704 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.43 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11104105 | 0.84 | MAOB (0.53) | MAOBALDH1A1LMNAKDM4ENPC1 | |
| SCHEMBL11100292 | 0.83 | ALDH1A1 (0.46) | ALDH1A1KDM4EMAPTACHEHTT | |
| SCHEMBL11108061 | 0.80 | LMNA (0.43) | ALDH1A1LMNAMAPTMAPK1HSD17B10 | |
| SCHEMBL11096932 | 0.79 | ALDH1A1 (0.49) | ALDH1A1LMNAKDM4ESMN1; SMN2MAPT | |
| SCHEMBL11105124 | 0.78 | MAOB (0.55) | MAOBALDH1A1LMNAKDM4ENPC1 | |
| SCHEMBL11180233 | 0.77 | ALDH1A1 (0.45) | ALDH1A1NPC1SMN1; SMN2RAB9AMAPT | |
| SCHEMBL11104730 | 0.76 | MAOB (0.46) | MAOBALDH1A1LMNAKDM4ENPC1 | |
| SCHEMBL11104724 | 0.76 | MAOB (0.46) | MAOBALDH1A1LMNAKDM4ENPC1 | |
| SCHEMBL5253082 | 0.74 | HTR1A (0.69) | MAOBALDH1A1LMNAKDM4ENPC1 | |
| Hydrochloric Acid SCHEMBL5248906 | 0.74 | HTR1A (0.68) | MAOBALDH1A1LMNAKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0029707-B1 | NOVEL PIPERIDINE DERIVATIVES, METHOD FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | KYOWA HAKKO KOGYO CO., LTD (JP) | 1984-02-01 | — | — | EP | disclosed |
| US-4390536-A | HYPOTENSIVE AGENTS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1983-06-28 | — | — | US | disclosed |
| US-4344945-A | HYPOTENSIVE AGENTS, BENZOXAZINYL DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1982-08-17 | — | — | US | disclosed |