Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | JAK2 | O60674 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 8/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | PDE5A | O76074 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11091669 | 0.92 | KDM4E (0.52) | KDM4EMAPTLMNAJAK2GAA | |
| SCHEMBL11090671 | 0.90 | KDM4E (0.50) | KDM4EMAPTLMNAJAK2GAA | |
| SCHEMBL6848695 | 0.89 | KDM4E (0.54) | KDM4EMAPTLMNAJAK2GAA | |
| SCHEMBL1545294 | 0.89 | L3MBTL1 (0.63) | MAPTLMNAGAAL3MBTL1TDP1 | |
| SCHEMBL10459169 | 0.89 | L3MBTL1 (0.63) | KDM4EMAPTLMNAL3MBTL1TDP1 | |
| Water SCHEMBL10556855 | 0.87 | L3MBTL1 (0.61) | MAPTLMNAGAAL3MBTL1TDP1 | |
| SCHEMBL5660214 | 0.85 | L3MBTL1 (0.59) | MAPTLMNAGAAL3MBTL1TDP1 | |
| SCHEMBL10459133 | 0.85 | HTR1A (0.57) | KDM4EMAPTL3MBTL1TDP1MAPK1 | |
| SCHEMBL10437664 | 0.85 | KCNA3 (0.46) | KDM4EMAPTLMNAJAK2GAA | |
| SCHEMBL5661298 | 0.84 | HTR7 (0.58) | KDM4EMAPTLMNAL3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0032063-B1 | NOVEL SUBSTITUTED ARYLENE COMPOUNDS AND PROCESSES FOR THEIR PRODUCTION | WARNER-LAMBERT COMPANY (US) | 1984-03-14 | — | — | EP | disclosed |
| US-4351950-A | Anti-arteriosclerotic agents | WARNER-LAMBERT COMPANY (US) | 1982-09-28 | — | — | US | disclosed |
| EP-0032063-A2 | Novel substituted arylene compounds and processes for their production | WARNER-LAMBERT COMPANY (US) | 1981-07-15 | — | — | EP | disclosed |