Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ACP1 | P24666 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 3/20 | 0.32 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.32 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.31 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18186488 | 0.84 | HTR6 (0.40) | HTR6TSHRCYP3A4RAPGEF4 | |
| SCHEMBL28982353 | 0.82 | HTR6 (0.39) | HTR6TSHRRAPGEF4 | |
| SCHEMBL29909475 | 0.82 | HTR6 (0.39) | HTR6RAPGEF4 | |
| SCHEMBL19089348 | 0.82 | HTR6 (0.39) | HTR6RAPGEF4 | |
| SCHEMBL24269714 | 0.82 | HTR6 (0.50) | HTR6TSHREGFREPHB2ERBB2 | |
| SCHEMBL16271800 | 0.78 | ALDH1A1 (0.42) | HTR6TSHRAPPCYP3A4TDP1 | |
| SCHEMBL24269920 | 0.77 | HTR6 (0.36) | HTR6 | |
| SCHEMBL13169800 | 0.77 | ACP1 (0.47) | ACP1RAPGEF4 | |
| SCHEMBL24270026 | 0.77 | HTR6 (0.36) | HTR6 | |
| SCHEMBL4410714 | 0.77 | TTR (0.39) | HTR6IDO1APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118159537-A | 6-Aza-quinoline derivatives and related uses | 黑钻治疗公司 | 2024-06-07 | — | — | CN | disclosed |
| CN-117396471-A | Novel piperidine derivatives and pharmaceutical compositions for inhibiting autotaxin comprising the same | 株式会社次代生物科学 | 2024-01-12 | — | — | CN | disclosed |
| CN-111517902-B | Aerobic oxidation system containing sulfinic acid, sulfonic acid or derivatives thereof and photo-oxidation promoting method thereof | 清华大学 | 2022-06-14 | — | — | CN | disclosed |
| CN-111517902-A | Aerobic oxidation system containing sulfinic acid, sulfonic acid or derivatives thereof and photo-oxidation promoting method thereof | 清华大学 | 2020-08-11 | — | — | CN | disclosed |
| WO-2020155595-A1 | AEROBIC OXIDATION SYSTEM CONTAINING SULFINIC ACID, SULFONIC ACID OR DERIVATIVES THEREOF AND PHOTOCATALYTIC OXIDATION METHOD THEREFOR | 清华大学 | 2020-08-06 | — | — | WO | disclosed |
| WO-2017141049-A1 | METHYLAMINE DERIVATIVES AS LYSYSL OXIDASE INHIBITORS FOR THE TREATMENT OF CANCER | THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) | 2017-08-24 | — | — | WO | disclosed |
| CN-102143966-B | Fluorine-containing boronic acid ester compound and method for producing same | UNIMATEC CO LTD | 2014-03-05 | — | — | CN | disclosed |
| EP-2325188-B1 | FLUORINE-CONTAINING BORONIC ACID ESTER COMPOUND AND METHOD FOR PRODUCING SAME | UNIMATEC CO LTD (JP) | 2013-06-05 | — | — | EP | disclosed |
| US-8044221-B2 | Fluorine-containing boronic acid ester compound and method for producing the same | UNIMATEC CO., LTD. (JP) | 2011-10-25 | — | — | US | disclosed |
| US-7977510-B2 | Fluorine-containing polyether compound and process for producing the same | UNIMATEC CO., LTD. (JP) | 2011-07-12 | — | — | US | disclosed |
| US-20110166375-A1 | FLUORINE-CONTAINING BORONIC ACID ESTER COMPOUND AND METHOD FOR PRODUCING THE SAME | UNIMATEC CO., LTD. (JP) | 2011-07-07 | — | — | US | disclosed |
| EP-2325188-A1 | FLUORINE-CONTAINING BORONIC ACID ESTER COMPOUND AND METHOD FOR PRODUCING SAME | Unimatec Co., Ltd. (JP) | 2011-05-25 | — | — | EP | disclosed |
| US-20110034729-A1 | FLUORINE-CONTAINING POLYETHER COMPOUND AND PROCESS FOR PRODUCING THE SAME | UNIMATEC CO., LTD. (JP) | 2011-02-10 | — | — | US | disclosed |
| EP-2280037-A1 | FLUORINE-CONTAINING POLYETHER COMPOUND AND METHOD FOR PRODUCING THE SAME | Unimatec Co., Ltd. (JP) | 2011-02-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110034729-A1 | FLUORINE-CONTAINING POLYETHER COMPOUND AND PROCESS FOR PRODUCING THE SAME | PBRM1, RIF1, RNF5 | HTR6 2345/4885TSHR 6/4885ACP1 4498/4885 |
| US-20110166375-A1 | FLUORINE-CONTAINING BORONIC ACID ESTER COMPOUND AND METHOD FOR PRODUCING THE SAME | BCL6, FGFR1, AFF1 | HTR6 3156/4885TSHR 283/4885ACP1 2763/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.