SCHEMBL1109757

SCHEMBL1109757

C=C(C)c1c(C)cc(C)cc1C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 2/20 0.38
ALDH1A1 P00352 3/20 0.37
KDM4E B2RXH2 3/20 0.37
LMNA P02545 2/20 0.37
GAA P10253 1/20 0.37
MAPT P10636 1/20 0.37
TP53 P04637 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
TAS1R3 Q7RTX0 2/20 0.34
TAS1R1 Q7RTX1 2/20 0.34
TAS1R2 Q8TE23 2/20 0.34
HPGD P15428 2/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
SELL P14151 1/20 0.33
SELP P16109 1/20 0.33
SELE P16581 1/20 0.33
CA1 P00915 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7915807 0.81 CYP3A4 (0.46) ALDH1A1LMNAGAATDP1HPGD
SCHEMBL7527264 0.80 RAPGEF4 (0.39) RAPGEF4ALDH1A1KDM4ELMNAGAA
SCHEMBL12726829 0.78 KMT2A (0.41) RAPGEF4ALDH1A1KDM4ELMNAGAA
SCHEMBL2722808 0.77 RAPGEF4 (0.41) RAPGEF4ALDH1A1KDM4ELMNAGAA
SCHEMBL918995 0.77 RAPGEF4 (0.41) RAPGEF4ALDH1A1KDM4ELMNAGAA
SCHEMBL918994 0.77 RAPGEF4 (0.41) RAPGEF4ALDH1A1KDM4ELMNAGAA
SCHEMBL27358236 0.76
SCHEMBL7705519 0.76 RAPGEF4 (0.36) RAPGEF4ALDH1A1KDM4ELMNAGAA
SCHEMBL28994798 0.75 TAS1R3 (0.34) RAPGEF4ALDH1A1KDM4ELMNAGAA
SCHEMBL24146231 0.75 CYP3A4 (0.48) ALDH1A1KDM4ELMNAGAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9296832-B2 Anionic polymerization methods for producing functionalized polymers BRIDGESTONE CORPORATION (JP) 2016-03-29 US claimed
EP-2504365-B1 ANIONIC POLYMERIZATION METHODS FOR PRODUCING FUNCTIONALIZED POLYMERS BRIDGESTONE CORP (JP) 2014-05-14 EP claimed
US-20130030133-A1 ANIONIC POLYMERIZATION METHODS FOR PRODUCING FUNCTIONALIZED POLYMERS BRIDGESTONE CORPORATION (JP) 2013-01-31 US claimed
US-11771172-B2 Shoe-forming member and shoe ASICS CORPORATION (JP) 2023-10-03 US disclosed
CN-112203549-B Shoes with removable sole 株式会社爱世克私 2021-10-29 CN disclosed
US-20210321714-A1 SHOE ASICS CORPORATION (JP) 2021-10-21 US disclosed
US-20210153598-A1 SHOE-FORMING MEMBER AND SHOE ASICS CORP (JP) 2021-05-27 US disclosed
US-10939725-B2 Shoe-forming member and shoe ASICS CORPORATION 2021-03-09 US disclosed
CN-112203549-A Shoes with removable sole 株式会社爱世克私 2021-01-08 CN disclosed
EP-3187062-B1 SHOE-FORMATION MEMBER AND SHOE ASICS CORP (JP) 2020-11-04 EP disclosed
US-20170273399-A1 SHOE-FORMING MEMBER AND SHOE ASICS CORPORATION (JP) 2017-09-28 US disclosed
US-20030120016-A1 Silalkylene oligosiloxane surface treating agent and process for preparation DOW CORNING TORAY SILICONE, CO. LTD. (JP) 2003-06-26 US disclosed
US-6380301-B1 CONTAINING SURFACE TREATED FILLER DOW CORNING TORAY SILICONE CO., LTD. (JP) 2002-04-30 US disclosed
US-6376635-B1 USING HYDROSILATION CATALYST DOW CORNING TORAY SILICON CO., LTD. (JP) 2002-04-23 US disclosed
US-20020010245-A1 Thermally conductive silicone rubber composition DOW CORNING TORAY SILICON, CO., LTD. (JP) 2002-01-24 US disclosed
EP-1162239-A2 Thermally conductive silicone rubber composition Dow Corning Toray Silicone Co., Ltd. (JP) 2001-12-12 EP disclosed
EP-1162203-A1 Silalkylene oligosiloxane surface treating agents and process for their preparation Dow Corning Toray Silicone Co., Ltd. (JP) 2001-12-12 EP disclosed
EP-1101767-A2 Oligosiloxane and method of preparing same Dow Corning Toray Silicone Co., Ltd. (JP) 2001-05-23 EP disclosed
EP-1101798-A2 Thermally conductive silicone rubber composition Dow Corning Toray Silicone Co., Ltd. (JP) 2001-05-23 EP disclosed
US-6124070-A STABILITY UNDER HIGH HUMIDITY AND AT LOW TEMPERATURE-LOW HUMIDITY, FINE PARTICLE SIZE AND A SHARP PARTICLE DIAMETER DISTRIBUTION; COMPRISING A BINDER RESIN, A COLORANT, A METHANOL-SOLUBLE RESIN HAVING ORGANIC ACID GROUPS CANON KABUSHIKI KAISHA (JP) 2000-09-26 US disclosed