Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.36 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.36 |
| ▸ | SELL | P14151 | 1/20 | 0.36 |
| ▸ | SELP | P16109 | 1/20 | 0.36 |
| ▸ | SELE | P16581 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL918994 | 1.00 | RAPGEF4 (0.41) | RAPGEF4ALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL4729778 | 0.88 | RAPGEF4 (0.38) | RAPGEF4ALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL2722808 | 0.81 | RAPGEF4 (0.41) | RAPGEF4ALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL2848308 | 0.78 | RAPGEF4 (0.43) | RAPGEF4ALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL13756307 | 0.77 | RAPGEF4 (0.38) | RAPGEF4ALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL698413 | 0.77 | KDM4E (0.46) | ALDH1A1KDM4ELMNAMAPTTAS1R3 | |
| SCHEMBL1109757 | 0.77 | RAPGEF4 (0.38) | RAPGEF4ALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL4334415 | 0.77 | RAPGEF4 (0.38) | RAPGEF4ALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL29162869 | 0.77 | PRSS1 (0.39) | RAPGEF4ALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL29169369 | 0.75 | KDM4E (0.44) | ALDH1A1KDM4ELMNAMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7875408-B2 | comprising photobleachable organic materials can be bleached by 193 nm light, and brought back to their original state by stimuli after exposure; to improve the aerial image effectively seen by the photoresist and thereby improve the contrast | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2011-01-25 | — | — | US | disclosed |
| US-20080182178-A1 | Bleachable materials for lithography | GLOBALFOUNDRIES U.S. INC. | 2008-07-31 | — | — | US | disclosed |