Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TPMT | P51580 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.36 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | SELL | P14151 | 1/20 | 0.36 |
| ▸ | SELP | P16109 | 1/20 | 0.36 |
| ▸ | SELE | P16581 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL918995 | 0.81 | RAPGEF4 (0.41) | RAPGEF4KDM4EALDH1A1LMNAGAA | |
| SCHEMBL918994 | 0.81 | RAPGEF4 (0.41) | RAPGEF4KDM4EALDH1A1LMNAGAA | |
| SCHEMBL2848308 | 0.78 | RAPGEF4 (0.43) | RAPGEF4KDM4EALDH1A1LMNAGAA | |
| SCHEMBL21870 | 0.77 | KDM4E (0.55) | KDM4EALDH1A1LMNAMAPTL3MBTL1 | |
| SCHEMBL698413 | 0.77 | KDM4E (0.46) | KDM4EALDH1A1LMNAMAPTL3MBTL1 | |
| SCHEMBL4334415 | 0.77 | RAPGEF4 (0.38) | RAPGEF4KDM4EALDH1A1LMNAGAA | |
| SCHEMBL377596 | 0.77 | KDM4E (0.55) | KDM4EALDH1A1LMNAMAPTL3MBTL1 | |
| SCHEMBL13756307 | 0.77 | RAPGEF4 (0.38) | RAPGEF4KDM4EALDH1A1LMNAGAA | |
| SCHEMBL4729778 | 0.77 | RAPGEF4 (0.38) | RAPGEF4KDM4EALDH1A1LMNAGAA | |
| SCHEMBL29162869 | 0.77 | PRSS1 (0.39) | RAPGEF4KDM4EALDH1A1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10451967-B2 | Acid- and radical-generating agent and method for generating acid and radical | FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) | 2019-10-22 | — | — | US | disclosed |
| US-20160342084-A1 | ACID- AND RADICAL-GENERATING AGENT AND METHOD FOR GENERATING ACID AND RADICAL | FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) | 2016-11-24 | — | — | US | disclosed |
| EP-2632929-A1 | N-HETEROCYCLIC CARBENE COMPLEXES, THEIR PREPARATION AND USE | BASF SE (DE) | 2013-09-04 | — | — | EP | disclosed |
| WO-2012056419-A1 | N-HETEROCYCLIC CARBENE COMPLEXES, THEIR PREPARATION AND USE | BASF SE (DE) | 2012-05-03 | — | — | WO | disclosed |
| US-7002010-B2 | Process for the preparation of morpholinones as light stabilizers | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2006-02-21 | — | — | US | disclosed |
| US-20040024252-A1 | Process for the preparation of morpholinones as light stabilizers | CIBA SPECIALTY CHEMICALS CORP. | 2004-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040024252-A1 | Process for the preparation of morpholinones as light stabilizers | TMT1A, SEM1, MITF | RAPGEF4 4706/4885KDM4E 167/4885ALDH1A1 34/4885 |
| US-10451967-B2 | Acid- and radical-generating agent and method for generating acid and radical | CBR1, HAO2, CBR3 | RAPGEF4 998/4885KDM4E 4342/4885ALDH1A1 151/4885 |
| US-20160342084-A1 | ACID- AND RADICAL-GENERATING AGENT AND METHOD FOR GENERATING ACID AND RADICAL | CBR1, HAO2, CBR3 | RAPGEF4 998/4885KDM4E 4342/4885ALDH1A1 151/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.