Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | MIF | P14174 | 1/20 | 0.42 |
| ▸ | TYR | P14679 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 5/20 | 0.41 |
| ▸ | RARB | P10826 | 2/20 | 0.41 |
| ▸ | RARG | P13631 | 2/20 | 0.41 |
| ▸ | RARA | P10276 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.38 |
| ▸ | ESRRA | P11474 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2338216 | 0.79 | ALDH1A1 (0.52) | ALDH1A1ALOX15HSD17B10NR1I2LMNA | |
| SCHEMBL3870569 | 0.78 | ALDH1A1 (0.41) | ALDH1A1ALOX15HSD17B10NR1I2LMNA | |
| SCHEMBL11097573 | 0.75 | MAOB (0.39) | ALDH1A1HTTMAPTMEN1CYP3A4 | |
| SCHEMBL2641096 | 0.74 | XDH (0.61) | ALDH1A1ALOX15HSD17B10NR1I2LMNA | |
| SCHEMBL29215518 | 0.74 | PELI1 (0.52) | ALDH1A1ALOX15HSD17B10NR1I2LMNA | |
| SCHEMBL10519843 | 0.74 | GAA (0.48) | ALDH1A1ALOX15HSD17B10NR1I2LMNA | |
| SCHEMBL11579939 | 0.73 | ALDH1A1 (0.45) | ALDH1A1ALOX15HSD17B10NR1I2LMNA | |
| SCHEMBL11579944 | 0.73 | ALDH1A1 (0.45) | ALDH1A1ALOX15HSD17B10NR1I2LMNA | |
| SCHEMBL10950826 | 0.72 | ALDH1A1 (0.55) | ALDH1A1ALOX15HSD17B10NR1I2LMNA | |
| SCHEMBL9073479 | 0.72 | NOS1 (0.44) | LMNAPTGS2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1729176-B1 | POSITIVE RADIATION-SENSITIVE RESIN COMPOSITION | JSR CORP (JP) | 2017-06-28 | — | — | EP | disclosed |
| US-7482111-B2 | Negative radiation-sensitive resin composition | JSR CORPORATION (JP) | 2009-01-27 | — | — | US | disclosed |
| US-20070190450-A1 | Negative radiation-sensitive resin composition | JSR CORPORATION (JP) | 2007-08-16 | — | — | US | disclosed |
| US-20070190465-A1 | Positively radiation-sensitive resin composition | JSR CORPORATION (JP) | 2007-08-16 | — | — | US | disclosed |
| EP-1746461-A1 | NEGATIVE RADIATION-SENSITIVE RESIN COMPOSITION | JSR Corporation (JP) | 2007-01-24 | — | — | EP | disclosed |
| EP-1729176-A1 | POSITIVELY RADIATION-SENSITIVE RESIN COMPOSITION | JSR Corporation (JP) | 2006-12-06 | — | — | EP | disclosed |