Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11266772 | 0.79 | LTA4H (0.48) | LTA4HCYP3A4SIGMAR1CXCR4L3MBTL1 | |
| SCHEMBL24976330 | 0.77 | LTA4H (0.46) | LTA4HCYP3A4SIGMAR1CXCR4 | |
| SCHEMBL24975784 | 0.77 | LTA4H (0.46) | LTA4HCYP3A4SIGMAR1CXCR4 | |
| SCHEMBL4851071 | 0.72 | LTA4H (0.51) | LTA4HCYP3A4SIGMAR1CXCR4L3MBTL1 | |
| SCHEMBL11094109 | 0.68 | LTA4H (0.58) | LTA4HCYP3A4CXCR4L3MBTL1ALDH1A1 | |
| SCHEMBL24135073 | 0.66 | SIGMAR1 (0.50) | CYP3A4SIGMAR1ALDH1A1 | |
| SCHEMBL24976021 | 0.66 | L3MBTL1 (0.53) | LTA4HCYP3A4CXCR4L3MBTL1ALDH1A1 | |
| SCHEMBL24977220 | 0.66 | L3MBTL1 (0.53) | LTA4HCYP3A4CXCR4L3MBTL1ALDH1A1 | |
| SCHEMBL24975769 | 0.66 | L3MBTL1 (0.53) | LTA4HCYP3A4CXCR4L3MBTL1ALDH1A1 | |
| SCHEMBL19582434 | 0.65 | SIGMAR1 (0.58) | LTA4HSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0031219-B1 | ANILINE DERIVATIVES | BEECHAM GROUP PLC (GB) | 1984-03-07 | — | — | EP | disclosed |