Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 1/20 | 0.47 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.43 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10892636 | 1.00 | FPR2 (0.47) | FPR2ITGB1ITGA4HDAC3HDAC4 | |
| SCHEMBL11097657 | 0.86 | GRIA1 (0.48) | GAACTSSCTSKTRPV1 | |
| SCHEMBL10892650 | 0.86 | GRIA1 (0.48) | GAACTSSCTSKTRPV1 | |
| SCHEMBL11207110 | 0.80 | CTSS (0.44) | FPR2CTSSCTSK | |
| SCHEMBL10608748 | 0.80 | CTSS (0.59) | CTSSCTSK | |
| SCHEMBL11209492 | 0.76 | LMNA (0.48) | CTSSCTSKHPGD | |
| SCHEMBL191156 | 0.74 | HDAC1 (0.58) | ITGB1ITGA4HDAC3HDAC4HDAC1 | |
| SCHEMBL2156643 | 0.74 | HDAC1 (0.58) | ITGB1ITGA4HDAC3HDAC4HDAC1 | |
| SCHEMBL191155 | 0.74 | HDAC1 (0.58) | ITGB1ITGA4HDAC3HDAC4HDAC1 | |
| SCHEMBL12463526 | 0.73 | HDAC1 (0.67) | HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0117089-A1 | Beta-adrenergic antagonist compounds and derivatives of beta-adrenergic antagonists | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1984-08-29 | — | — | EP | disclosed |