Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 2/20 | 0.48 |
| ▸ | SRC | P12931 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CHRND | Q07001 | 5/20 | 0.43 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.43 |
| ▸ | CHRNG | P07510 | 1/20 | 0.43 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10892650 | 1.00 | GRIA1 (0.48) | GRIA1SRCTRPV1PTPN1GAA | |
| SCHEMBL10892636 | 0.86 | FPR2 (0.47) | TRPV1GAACTSSCTSK | |
| SCHEMBL11097650 | 0.86 | FPR2 (0.47) | TRPV1GAACTSSCTSK | |
| SCHEMBL11207112 | 0.79 | GRIA1 (0.59) | GRIA1SRCPTPN1CHRNDCHRNA1 | |
| SCHEMBL10608759 | 0.79 | CTSS (0.67) | GRIA1SRCPTPN1CTSSCTSK | |
| SCHEMBL11209498 | 0.75 | GRIA1 (0.52) | GRIA1SRCPTPN1CTSSCTSK | |
| SCHEMBL191155 | 0.74 | HDAC1 (0.58) | — | |
| SCHEMBL2156643 | 0.74 | HDAC1 (0.58) | — | |
| SCHEMBL191156 | 0.74 | HDAC1 (0.58) | — | |
| SCHEMBL14567242 | 0.72 | CTSS (0.68) | SRCCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0117089-A1 | Beta-adrenergic antagonist compounds and derivatives of beta-adrenergic antagonists | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1984-08-29 | — | — | EP | disclosed |