Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20133901 | 0.83 | KMT2A (0.51) | KMT2ATSHRGAAPTGS1PTGS2 | |
| SCHEMBL8596103 | 0.79 | HSD17B10 (0.43) | KMT2AALDH1A1LMNAGLATDP1 | |
| SCHEMBL2417683 | 0.73 | TDP1 (0.56) | KMT2ATSHRGAAALDH1A1LMNA | |
| SCHEMBL11098132 | 0.73 | NPC1 (0.42) | KMT2AGAALMNANPC1RAB9A | |
| SCHEMBL8845741 | 0.72 | KMT2A (0.55) | KMT2ATSHRGAAPTGS1PTGS2 | |
| SCHEMBL2097359 | 0.72 | KMT2A (0.55) | KMT2ATSHRGAAPTGS1PTGS2 | |
| SCHEMBL8980460 | 0.71 | KMT2A (0.46) | KMT2AGAAHTTLMNACYP3A4 | |
| SCHEMBL16453798 | 0.71 | KMT2A (0.53) | KMT2ATSHRGAAPTGS1PTGS2 | |
| SCHEMBL6662043 | 0.71 | KMT2A (0.53) | KMT2ATSHRGAAPTGS1PTGS2 | |
| SCHEMBL7735376 | 0.71 | KMT2A (0.53) | KMT2ATSHRGAAPTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4444690-A | RADIOPHARMACEUTICALS FOR MAMMALIAN RENAL SYSTEMS | UNIVERSITY PATENTS, INC. (US) | 1984-04-24 | — | — | US | disclosed |