Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CES1 | P23141 | 2/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | ATM | Q13315 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8595093 | 0.81 | ACE (0.51) | KMT2ALMNAALKBH5MDM2TDP1 | |
| SCHEMBL2028236 | 0.76 | ACE (0.47) | KMT2ALMNATDP1MAPTMAPK1 | |
| SCHEMBL7745199 | 0.76 | ACE (0.47) | KMT2ALMNATDP1MAPTMAPK1 | |
| SCHEMBL2417683 | 0.75 | TDP1 (0.56) | KMT2ACES1CES2LMNAALKBH5 | |
| SCHEMBL9067249 | 0.75 | GPR139 (0.47) | KMT2AMEN1ACE | |
| SCHEMBL237683 | 0.74 | GAA (0.63) | LMNANPC1RAB9AGAASMN1; SMN2 | |
| SCHEMBL10720961 | 0.73 | KMT2A (0.38) | KMT2AMDM2NPC1RAB9AATM | |
| SCHEMBL9067258 | 0.72 | SLC1A1 (0.39) | KMT2AACE | |
| SCHEMBL5274104 | 0.72 | TDP1 (0.52) | CES1CES2LMNAALKBH5PGR | |
| SCHEMBL7207824 | 0.72 | TDP1 (0.52) | CES1CES2LMNAALKBH5PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0710228-A1 | HYDRAZINO-TYPE RADIONUCLIDE CHELATORS HAVING AN N 3?S CONFIGURATION | RESOLUTION PHARMACEUTICALS INC. (CA) | 1996-05-08 | — | — | EP | disclosed |
| WO-1995003280-A1 | HYDRAZINO-TYPE RADIONUCLIDE CHELATORS HAVING AN N3S CONFIGURATION | RESOLUTION PHARMACEUTICALS INC. (CA) | 1995-02-02 | — | — | WO | disclosed |