Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.40 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.40 |
| ▸ | MEP1B | Q16820 | 2/20 | 0.39 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.39 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.39 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.39 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12158277 | 0.81 | LMNA (0.61) | HSD17B10LMNATDP1ALDH1A1KMT2A | |
| SCHEMBL11097672 | 0.79 | KMT2A (0.44) | HSD17B10LMNATDP1ALDH1A1THRB | |
| SCHEMBL20133901 | 0.75 | KMT2A (0.51) | LMNATDP1ALDH1A1KMT2A | |
| SCHEMBL9398218 | 0.75 | MME (0.38) | HSD17B10LMNATDP1ALDH1A1CYP2C19 | |
| SCHEMBL15471556 | 0.75 | KMT2A (0.49) | HSD17B10LMNATDP1ALDH1A1CYP2C19 | |
| SCHEMBL8596105 | 0.74 | GPR139 (0.56) | HSD17B10LMNATDP1ALDH1A1KMT2A | |
| SCHEMBL19177610 | 0.73 | GNPAT (0.57) | HSD17B10ALDH1A1THRBCYP2C9CYP2C19 | |
| SCHEMBL11098132 | 0.73 | NPC1 (0.42) | LMNAKMT2A | |
| SCHEMBL11913605 | 0.73 | KMT2A (0.51) | HSD17B10LMNATDP1ALDH1A1CYP2C19 | |
| SCHEMBL28502817 | 0.73 | POLB (0.51) | ALDH1A1KMT2ANAALAD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0710228-B1 | HYDRAZINO-TYPE RADIONUCLIDE CHELATORS HAVING AN N 3?S CONFIGURATION | RESOLUTION PHARM INC (CA) | 1998-01-21 | — | — | EP | disclosed |
| US-5659041-A | MEDICAL DIAGNOSIS, THERAPY | RESOLUTION PHARMACEUTICALS, INC. (CA) | 1997-08-19 | — | — | US | disclosed |
| EP-0710228-A1 | HYDRAZINO-TYPE RADIONUCLIDE CHELATORS HAVING AN N 3?S CONFIGURATION | RESOLUTION PHARMACEUTICALS INC. (CA) | 1996-05-08 | — | — | EP | disclosed |
| WO-1995003280-A1 | HYDRAZINO-TYPE RADIONUCLIDE CHELATORS HAVING AN N3S CONFIGURATION | RESOLUTION PHARMACEUTICALS INC. (CA) | 1995-02-02 | — | — | WO | disclosed |