SCHEMBL2097359

SCHEMBL2097359

COC(=O)C(C(=O)OC)C(=O)c1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.55
TSHR P16473 1/20 0.54
PTGS1 P23219 1/20 0.47
PTGS2 P35354 1/20 0.47
TDP1 Q9NUW8 2/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
GAA P10253 1/20 0.46
ALDH1A1 P00352 2/20 0.46
CYP3A4 P08684 1/20 0.46
CES2 O00748 1/20 0.45
LMNA P02545 1/20 0.45
CES1 P23141 1/20 0.45
SRC P12931 1/20 0.44
KDM4E B2RXH2 1/20 0.43
ESRRB O95718 1/20 0.43
PGR P06401 1/20 0.43
ADRA2A P08913 1/20 0.43
ADRA2B P18089 1/20 0.43
HTR2A P28223 1/20 0.43
HRH1 P35367 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8845741 0.96 KMT2A (0.55) KMT2ATSHRPTGS1PTGS2TDP1
SCHEMBL5706065 0.92 KMT2A (0.51) KMT2ATSHRPTGS1PTGS2TDP1
SCHEMBL28780782 0.90 KMT2A (0.50) KMT2ATSHRPTGS1PTGS2TDP1
SCHEMBL16502242 0.84 KMT2A (0.45) KMT2ATSHRPTGS1PTGS2TDP1
SCHEMBL16453798 0.82 KMT2A (0.53) KMT2ATSHRPTGS1PTGS2TDP1
SCHEMBL7735376 0.82 KMT2A (0.53) KMT2ATSHRPTGS1PTGS2TDP1
SCHEMBL6662043 0.82 KMT2A (0.53) KMT2ATSHRPTGS1PTGS2TDP1
SCHEMBL5936619 0.80 KMT2A (0.51) KMT2ATSHRPTGS1PTGS2TDP1
SCHEMBL6618828 0.80 KMT2A (0.51) KMT2ATSHRPTGS1PTGS2TDP1
SCHEMBL20133901 0.80 KMT2A (0.51) KMT2ATSHRPTGS1PTGS2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109678997-B Catalyst component and catalyst for olefin polymerization, prepolymerized catalyst and olefin polymerization method 中国石油化工股份有限公司 2021-11-19 CN disclosed
US-8372300-B2 Additives for electrolyte solution and electrolyte solution OTSUKA CHEMICAL CO., LTD. (JP) 2013-02-12 US disclosed
US-20120170172-A1 ADDITIVES FOR ELECTROLYTE SOLUTION AND ELECTROLYTE SOLUTION OKA AKINORI (JP) 2012-07-05 US disclosed
US-8163195-B2 Additives for electrolyte solution and electrolyte solution OTSUKA CHEMICAL CO., LTD. (JP) 2012-04-24 US disclosed
US-20090309060-A1 Additives for Electrolyte Solution and Electrolyte Solution OTSUKA CHEMICAL CO., LTD. (JP) 2009-12-17 US disclosed
EP-2037468-A1 ADDITIVE FOR ELECTROLYTE SOLUTION AND ELECTROLYTE SOLUTION Otsuka Chemical Co., Ltd. (JP) 2009-03-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090309060-A1 Additives for Electrolyte Solution and Electrolyte Solution SLC9A1, SLC26A3, AQP1 KMT2A 1260/4885TSHR 4478/4885PTGS1 4365/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.