Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5180445 | 0.83 | ELANE (0.51) | HSD11B1ELANEABL1KMT2ARIN1 | |
| SCHEMBL1828953 | 0.79 | TDP1 (0.41) | HSD11B1ELANEKMT2AMAPTALDH1A1 | |
| SCHEMBL1603072 | 0.79 | HSD11B1 (0.49) | HSD11B1ABL1KMT2ARIN1MAPT | |
| Malonic Acid SCHEMBL6825034 | 0.75 | ELANE (0.43) | ELANEKMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL8406338 | 0.70 | TDP1 (0.38) | LMNAALDH1A1HSD17B10HPGD | |
| SCHEMBL11100800 | 0.70 | NQO1 (0.44) | MAPTLMNAALDH1A1HSD17B10HPGD | |
| SCHEMBL3428777 | 0.69 | LMNA (0.52) | HSD11B1ABL1KMT2ARIN1MAPT | |
| SCHEMBL1719139 | 0.66 | HTR7 (0.41) | HSD11B1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL11100337 | 0.66 | NQO1 (0.47) | MAPTLMNAALDH1A1HSD17B10HPGD | |
| SCHEMBL15016524 | 0.66 | GLA (0.39) | HSD11B1ABL1KMT2ARIN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4457911-A | Dialkyl malonates as organic sunscreen adjuvants | VAN DYK & COMPANY INC. (US) | 1984-07-03 | — | — | US | disclosed |