Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | PDE9A | O76083 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.34 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA3 | P07451 | 2/20 | 0.33 |
| ▸ | CA4 | P22748 | 2/20 | 0.33 |
| ▸ | CA6 | P23280 | 2/20 | 0.33 |
| ▸ | CA7 | P43166 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1828953 | 0.90 | TDP1 (0.41) | TDP1PDE2APDE9ACYP2C19ALDH1A1 | |
| SCHEMBL8406468 | 0.88 | ALDH1A1 (0.34) | PDE2AKDM4EALDH1A1CA2LMNA | |
| SCHEMBL11097871 | 0.70 | HSD11B1 (0.38) | ALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL5180445 | 0.68 | ELANE (0.51) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL28033428 | 0.68 | BDKRB2 (0.45) | TDP1AKR1C3AKR1C2AKR1C1PTGS1 | |
| SCHEMBL8406246 | 0.64 | TSHR (0.39) | TDP1ALDH1A1CA2TAS1R3TAS1R1 | |
| SCHEMBL9893490 | 0.62 | ALDH1A1 (0.45) | TDP1ALDH1A1CA2LMNA | |
| SCHEMBL22499622 | 0.62 | TDP1 (0.46) | TDP1CA12CA1CA3CA4 | |
| SCHEMBL1603072 | 0.62 | HSD11B1 (0.49) | CA12CA1CA7CA9CA14 | |
| Malonic Acid SCHEMBL6825034 | 0.61 | ELANE (0.43) | KDM4EALDH1A1HPGDHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0663206-B1 | Naphthalenmethylenemalonic diesters, and UV absorbers and cosmetic compositions containing the diesters | KAO CORP (JP) | 1999-07-14 | — | — | EP | disclosed |
| US-5508025-A | SUNSCREEN AGENTS | KAO CORPORATION (JP) | 1996-04-16 | — | — | US | disclosed |
| EP-0663206-A1 | Naphthalenmethylenemalonic diesters, and UV absorbers and cosmetic compositions containing the diesters | Kao Corporation (JP) | 1995-07-19 | — | — | EP | disclosed |