Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 5/20 | 0.37 |
| ▸ | JUN | P05412 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 5/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.35 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PLK4 | O00444 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
| ▸ | LTK | P29376 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11489657 | 0.79 | ALDH1A1 (0.38) | JUNNFKB1NFKB2RELA | |
| Hydrochloric Acid SCHEMBL11489660 | 0.79 | NAPRT (0.42) | JUNNFKB1NFKB2RELATDP1 | |
| SCHEMBL9484721 | 0.75 | TSHR (0.40) | JUNNFKB1NFKB2RELA | |
| SCHEMBL10776834 | 0.71 | KDM4E (0.35) | JUNNFKB1NFKB2RELATDP1 | |
| SCHEMBL2762235 | 0.68 | DGAT1 (0.42) | NNMTPARP1MAP4K4SIRT3TDP1 | |
| SCHEMBL30641935 | 0.68 | DGAT1 (0.42) | NNMTPARP1MAP4K4SIRT3TDP1 | |
| SCHEMBL23835352 | 0.68 | NNMT (0.45) | NNMTMAP4K4CSF1R | |
| SCHEMBL29920919 | 0.67 | DGAT1 (0.41) | NNMTPARP1MAP4K4DGAT1JAK2 | |
| SCHEMBL6940087 | 0.67 | GABRP (0.46) | NNMTPARP1MAP4K4SIRT3TDP1 | |
| SCHEMBL15095256 | 0.66 | SIRT3 (0.43) | NNMTPARP1MAP4K4SIRT3TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0128316-A1 | Reactive disazo dyes | BAYER AG (DE) | 1984-12-19 | — | — | EP | disclosed |
| US-4024123-A | TEXTILES | DUSSY PAUL | 1977-05-17 | — | — | US | disclosed |