Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 16/20 | 0.68 |
| ▸ | PARP15 | Q460N3 | 6/20 | 0.55 |
| ▸ | PARP4 | Q9UKK3 | 2/20 | 0.55 |
| ▸ | PARP14 | Q460N5 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.55 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.55 |
| ▸ | PARP2 | Q9UGN5 | 3/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | PARP1 | P09874 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 3/20 | 0.51 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1344671 | 0.84 | PARP10 (0.66) | PARP10PARP15PARP4PARP14ALDH1A1 | |
| SCHEMBL1109902 | 0.82 | PKM (0.69) | ALDH1A1 | |
| SCHEMBL77571 | 0.82 | PARP10 (0.70) | PARP10PARP15PARP4PARP14ALDH1A1 | |
| SCHEMBL6122034 | 0.82 | PARP10 (0.70) | PARP10PARP15PARP4PARP14ALDH1A1 | |
| SCHEMBL4687732 | 0.81 | PARP10 (0.68) | PARP10PARP15PARP4PARP14ALDH1A1 | |
| Hydrochloric Acid SCHEMBL12502964 | 0.81 | PARP10 (0.68) | PARP10PARP15PARP4PARP14ALDH1A1 | |
| SCHEMBL3085074 | 0.81 | PARP10 (0.68) | PARP10PARP15PARP4PARP14ALDH1A1 | |
| SCHEMBL4687508 | 0.81 | PARP10 (0.68) | PARP10PARP15PARP4PARP14ALDH1A1 | |
| Water SCHEMBL5055924 | 0.81 | PARP10 (0.68) | PARP10PARP15PARP4PARP14ALDH1A1 | |
| SCHEMBL1977030 | 0.81 | PARP10 (0.68) | PARP10PARP15PARP4PARP14ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120277275-A1 | AZOLE AND THIAZOLE DERIVATIVES AND THEIR USE | PULMAGEN THERAPEUTICS (SYNERGY) LIMITED (GB) | 2012-11-01 | — | — | US | disclosed |
| EP-2280006-A1 | PHARMACEUTICAL COMPOSITION FOR INHALATION COMPRISING AN OXAZOLE OR THIAZOLE M3 MUSCARINIC RECEPTOR ANTAGONIST | Pulmagen Therapeutics (Synergy) Limited (GB) | 2011-02-02 | — | — | EP | disclosed |
| EP-1924570-B1 | AZOLE AND THIAZOLE DERIVATIVES AND THEIR USE | PULMAGEN THERAPEUTICS SYNERGY (GB) | 2010-10-20 | — | — | EP | disclosed |
| US-20100113540-A1 | Azole and Thiazole Derivatives and Their Use | ARGENTA DISCOVERY LIMITED (GB) | 2010-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100113540-A1 | Azole and Thiazole Derivatives and Their Use | CHRM3, CHRM2, CHRM1 | PARP10 1868/4885PARP15 3326/4885PARP4 4270/4885 |
| US-20120277275-A1 | AZOLE AND THIAZOLE DERIVATIVES AND THEIR USE | CHRM3, GPR65, GPR34 | PARP10 3931/4885PARP15 3449/4885PARP4 4390/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.