Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 11/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 10/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 10/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 10/20 | 0.45 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12132801 | 0.79 | GRIN1 (0.37) | HTR1AGAAADRA1DADRA1AADRA1B | |
| SCHEMBL12132844 | 0.79 | GRIN1 (0.37) | HTR1AGAAADRA1DADRA1AADRA1B | |
| SCHEMBL12132845 | 0.79 | GRIN1 (0.37) | HTR1AGAAADRA1DADRA1AADRA1B | |
| SCHEMBL10807843 | 0.74 | GAA (0.49) | HTR1AGAAADRA1DADRA1AADRA1B | |
| SCHEMBL10759760 | 0.73 | TMEM97 (0.49) | HTR1AADRA1DADRA1AADRA1BTMEM97 | |
| SCHEMBL12132799 | 0.71 | HTR1A (0.34) | HTR1AADRA1DADRA1A | |
| SCHEMBL28130300 | 0.70 | HTR1A (0.47) | HTR1AADRA1DADRA1AADRA1BTMEM97 | |
| SCHEMBL12132821 | 0.68 | ADRA1A (0.36) | HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL12080250 | 0.68 | SIGMAR1 (0.58) | HTR1AGAAADRA1DADRA1AADRA1B | |
| SCHEMBL12133064 | 0.68 | CYP3A4 (0.46) | HTR1AADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0097822-A1 | Aminomethyldioxolanes as parasiticides | BAYER AG (DE) | 1984-01-11 | — | — | EP | disclosed |