Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 4/20 | 0.46 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11259848 | 0.91 | HTR1A (0.49) | HTR1ATMEM97SIGMAR1GRIN1GRIN2A | |
| Hydrochloric Acid SCHEMBL29449197 | 0.90 | HTR1A (0.48) | HTR1ATMEM97SIGMAR1GRIN1GRIN2A | |
| SCHEMBL27721335 | 0.78 | GRIN1 (0.44) | GRIN1GRIN2ACHRM2CHRM4CHRM5 | |
| SCHEMBL11099168 | 0.74 | HTR1A (0.46) | GAAHTR1ATMEM97SIGMAR1ADRA1D | |
| Oxapium SCHEMBL24857 | 0.72 | CTDSP1 (0.47) | GRIN1GRIN2ACHRM2CHRM4CHRM5 | |
| Oxapium SCHEMBL1316687 | 0.71 | CTDSP1 (0.49) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL10807846 | 0.71 | CHRM2 (0.39) | HTR1AGRIN1GRIN2AADRA1ACHRM2 | |
| Hydrochloric Acid SCHEMBL30904664 | 0.70 | HTR1A (0.67) | GAAHTR1ATMEM97SIGMAR1ADRA1D | |
| SCHEMBL14039627 | 0.69 | CHRM2 (0.43) | GRIN1GRIN2ACHRM2CHRM4CHRM5 | |
| SCHEMBL12080250 | 0.66 | SIGMAR1 (0.58) | GAAHTR1ATMEM97SIGMAR1ADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0097822-B1 | AMINOMETHYLDIOXOLANES AS PARASITICIDES | BAYER AG (DE) | 1987-07-15 | — | — | EP | disclosed |
| EP-0097822-A1 | Aminomethyldioxolanes as parasiticides | BAYER AG (DE) | 1984-01-11 | — | — | EP | disclosed |