Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14086384 | 0.64 | ALDH1A1 (0.48) | LMNAPOLBSMN1; SMN2MAPK1HTT | |
| SCHEMBL18786507 | 0.64 | ALDH1A1 (0.45) | LMNAPOLBSMN1; SMN2HTT | |
| SCHEMBL7866209 | 0.62 | CYP2D6 (0.34) | LMNAPOLBSMN1; SMN2MAPK1 | |
| SCHEMBL9615422 | 0.62 | LMNA (0.33) | LMNAPOLBSMN1; SMN2MAPK1HTT | |
| SCHEMBL8773370 | 0.59 | FURIN (0.43) | LMNAPOLBSMN1; SMN2MAPK1HTT | |
| SCHEMBL19386537 | 0.59 | — | — | |
| SCHEMBL8773373 | 0.59 | FURIN (0.43) | LMNAPOLBSMN1; SMN2MAPK1HTT | |
| SCHEMBL2430394 | 0.58 | CHRNB4 (0.39) | LMNASMN1; SMN2MAPK1 | |
| SCHEMBL10039078 | 0.57 | NPC1 (0.39) | SMN1; SMN2HTT | |
| SCHEMBL33542 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0033183-B1 | PHENYLIMINOMETHYL-3-PYRIDINE DERIVATIVES, THEIR PREPARATION AND USE | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1984-07-04 | — | — | EP | disclosed |
| EP-0033183-A2 | Phenyliminomethyl-3-pyridine derivatives, their preparation and use | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1981-08-05 | — | — | EP | disclosed |