Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7866209 | 0.70 | CYP2D6 (0.34) | LMNAPOLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL8755227 | 0.69 | CYP2D6 (0.33) | — | |
| SCHEMBL18786507 | 0.65 | ALDH1A1 (0.45) | LMNAPOLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL4799168 | 0.65 | KMT2A (0.34) | KMT2AALDH1A1 | |
| SCHEMBL11099215 | 0.62 | LMNA (0.33) | LMNAPOLBSMN1; SMN2HTTMAPK1 | |
| SCHEMBL8773370 | 0.60 | FURIN (0.43) | LMNAPOLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL8773373 | 0.60 | FURIN (0.43) | LMNAPOLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL1008703 | 0.59 | ATM (0.42) | POLBSMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL1008702 | 0.59 | ATM (0.42) | POLBSMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL6687850 | 0.59 | ALDH1A1 (0.38) | LMNAPOLBSMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4139425-A | — | — | None | — | — | JP | disclosed |
| JP-H04139425-A | NONLINEAR OPTICAL MATERIAL | NIPPON OIL & FATS CO LTD | 1992-05-13 | — | — | JP | disclosed |