Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 4/20 | 0.51 |
| ▸ | GALR3 | O60755 | 1/20 | 0.50 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | ERCC1 | P07992 | 2/20 | 0.42 |
| ▸ | ERCC4 | Q92889 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL838069 | 0.84 | ALDH1A1 (0.53) | P2RX7GALR3NR2F2L3MBTL1KMT2A | |
| SCHEMBL836320 | 0.83 | L3MBTL1 (0.62) | P2RX7GALR3NR2F2L3MBTL1KMT2A | |
| SCHEMBL2847244 | 0.82 | MAPT (0.55) | L3MBTL1EPHX2RECQLLMNAMAPK1 | |
| SCHEMBL5318479 | 0.79 | MAPT (0.57) | L3MBTL1KMT2AEPHX2LMNAMAPK1 | |
| SCHEMBL2119177 | 0.76 | MGAM (0.47) | P2RX7GALR3NR2F2KMT2AEPHX2 | |
| SCHEMBL11000136 | 0.76 | ERCC1 (0.48) | L3MBTL1KMT2AEPHX2RECQLERCC1 | |
| SCHEMBL10580138 | 0.76 | GGPS1 (0.44) | P2RX7GALR3NR2F2L3MBTL1KMT2A | |
| SCHEMBL11096668 | 0.75 | GALR3 (0.53) | P2RX7GALR3NR2F2KMT2ATSHR | |
| SCHEMBL20796876 | 0.74 | GALR3 (0.55) | P2RX7GALR3NR2F2L3MBTL1RECQL | |
| SCHEMBL28940593 | 0.74 | IDO1 (0.54) | P2RX7GALR3NR2F2L3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0117485-A2 | Pyridine, pyrazine and pyrimidine derivatives and their use as fungicides | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1984-09-05 | — | — | EP | disclosed |