Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.42 |
| ▸ | RELA | Q04206 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MERTK | Q12866 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11097842 | 0.80 | PIK3CG (0.44) | GRIA1MEN1KMT2ANPC1LMNA | |
| SCHEMBL11245974 | 0.80 | PDPK1 (0.36) | MAPTTSHRMAPK1MERTKPDPK1 | |
| SCHEMBL17042383 | 0.77 | MEN1 (0.51) | GRIA1MEN1KMT2ANPC1LMNA | |
| SCHEMBL12589727 | 0.76 | NPC1 (0.45) | GRIA1MEN1KMT2ANPC1LMNA | |
| SCHEMBL11121196 | 0.73 | MEN1 (0.37) | GRIA1MEN1KMT2ANPC1LMNA | |
| SCHEMBL11275692 | 0.72 | KMT2A (0.47) | GRIA1MEN1KMT2ANPC1LMNA | |
| SCHEMBL10913638 | 0.70 | NCF1 (0.58) | GRIA1MEN1KMT2ANPC1LMNA | |
| SCHEMBL2947867 | 0.69 | MEN1 (0.50) | GRIA1MEN1KMT2ANPC1LMNA | |
| SCHEMBL9480557 | 0.69 | MEN1 (0.50) | GRIA1MEN1KMT2ANPC1LMNA | |
| SCHEMBL10965212 | 0.69 | CASP1 (0.39) | GRIA1MEN1KMT2ANPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0024931-B1 | 1,2,4-BENZOTRIAZINYLAMINOPHENOXYALKANE CARBOXYLIC ACID DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES | ICI AUSTRALIA LIMITED (AU) | 1984-10-17 | — | — | EP | disclosed |
| US-4310347-A | Herbicidal 1,2,4-benzotriazines | ICI AUSTRALIA LIMITED (AU) | 1982-01-12 | — | — | US | disclosed |
| EP-0024931-A2 | 1,2,4-Benzotriazinylaminophenoxyalkane carboxylic acid derivatives, processes for their preparation and their use as herbicides | ICI AUSTRALIA LIMITED (AU) | 1981-03-11 | — | — | EP | disclosed |