SCHEMBL12589727

SCHEMBL12589727

CN(c1ccc(O)cc1)c1nc(N(C)c2ccc(O)cc2)nc(N(C)c2ccc(O)cc2)n1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 5/20 0.45
MEN1 O00255 4/20 0.45
KMT2A Q03164 4/20 0.45
RAB9A P51151 4/20 0.45
NFKB1 P19838 3/20 0.45
LMNA P02545 3/20 0.45
MAPT P10636 3/20 0.45
HPGD P15428 3/20 0.45
HSD17B10 Q99714 3/20 0.45
MAPK1 P28482 3/20 0.45
NFKB2 Q00653 2/20 0.45
RELA Q04206 2/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
TSHR P16473 2/20 0.45
USP2 O75604 1/20 0.45
TP53 P04637 1/20 0.45
MMP13 P45452 1/20 0.45
APP P05067 4/20 0.43
PTGS2 P35354 1/20 0.42
GRIA1 P42261 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17042383 0.92 MEN1 (0.51) NPC1MEN1KMT2ARAB9ANFKB1
SCHEMBL16698000 0.86 PTGS2 (0.44) NPC1MEN1KMT2ARAB9ANFKB1
SCHEMBL926427 0.82 APP (0.52) NPC1MEN1KMT2ARAB9ANFKB1
SCHEMBL12589721 0.81 NR1H2 (0.42) NPC1MEN1KMT2ARAB9ANFKB1
SCHEMBL22344857 0.80 CPT1B (0.38) NPC1MEN1KMT2ARAB9ANFKB1
SCHEMBL22356374 0.78 THRB (0.43) NPC1MEN1KMT2ARAB9ANFKB1
SCHEMBL11099340 0.76 GRIA1 (0.43) NPC1MEN1KMT2ARAB9ANFKB1
SCHEMBL11453774 0.76 HDAC6 (0.37) NPC1MEN1KMT2ARAB9ANFKB1
SCHEMBL11453631 0.76 PTGS2 (0.43) NPC1MEN1KMT2ARAB9ANFKB1
SCHEMBL8974883 0.75 TSHR (0.53) MEN1KMT2ALMNAMAPK1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025022768-A1 CYANATE ESTER COMPOUND AND METHOD FOR PRODUCING SAME, RESIN COMPOSITION, AND CURED PRODUCT 三菱瓦斯化学株式会社 2025-01-30 WO disclosed
WO-2025022769-A1 CYANATE ESTER COMPOUND AND METHOD FOR PRODUCING SAME, RESIN COMPOSITION, AND CURED PRODUCT 三菱瓦斯化学株式会社 2025-01-30 WO disclosed
CN-111065628-B Novel triazine derivative and photosensitive composition comprising the same 株式会社特雷尔 2023-06-02 CN disclosed
US-11427551-B2 Triazine derivative and photosensitive composition comprising same TREEEL CO., LTD (KR) 2022-08-30 US disclosed
US-20200262798-A1 NOVEL TRIAZINE DERIVATIVE AND PHOTOSENSITIVE COMPOSITION COMPRISING SAME TREEEL CO., LTD (KR) 2020-08-20 US disclosed
US-20200262798-A1 NOVEL TRIAZINE DERIVATIVE AND PHOTOSENSITIVE COMPOSITION COMPRISING SAME TREEEL CO., LTD (KR) 2020-08-20 US disclosed
EP-2913302-B1 CYANOGEN-HALIDE PRODUCTION METHOD, CYANATE ESTER COMPOUND AND PRODUCTION METHOD THEREFOR, AND RESIN COMPOSITION MITSUBISHI GAS CHEMICAL CO (JP) 2019-04-10 EP disclosed
WO-2019054707-A1 NOVEL TRIAZINE DERIVATIVE AND PHOTOSENSITIVE COMPOSITION COMPRISING SAME 주식회사 트리엘 2019-03-21 WO disclosed
US-9475761-B2 Method for producing cyanogen-halide, cyanate ester compound and method for producing the same, and resin composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2016-10-25 US disclosed
US-20150299110-A1 METHOD FOR PRODUCING CYANOGEN-HALIDE, CYANATE ESTER COMPOUND AND METHOD FOR PRODUCING THE SAME, AND RESIN COMPOSITION MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2015-10-22 US disclosed
EP-2913302-A1 CYANOGEN-HALIDE PRODUCTION METHOD, CYANATE ESTER COMPOUND AND PRODUCTION METHOD THEREFOR, AND RESIN COMPOSITION Mitsubishi Gas Chemical Company, Inc. (JP) 2015-09-02 EP disclosed
CN-104755422-A Method for producing cyanogen halide, cyanate ester compound and method for producing same, and resin composition MITSUBISHI GAS CHEMICAL CO 2015-07-01 CN disclosed
US-7956020-B2 Reducing friction between two moving surfaces; oil additive mixture FUJIFILM CORPORATION (JP) 2011-06-07 US disclosed
US-7956020-B2 Reducing friction between two moving surfaces; oil additive mixture FUJIFILM CORPORATION (JP) 2011-06-07 US disclosed
US-20080274920-A1 Reducing friction between two moving surfaces; oil additive mixture FUJIFILM CORPORATION (JP) 2008-11-06 US disclosed
US-20080274920-A1 Reducing friction between two moving surfaces; oil additive mixture FUJIFILM CORPORATION (JP) 2008-11-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150299110-A1 METHOD FOR PRODUCING CYANOGEN-HALIDE, CYANATE ESTER COMPOUND AND METHOD FOR PRODUCING THE SAME, AND RESIN COMPOSITION MB, CBR3, CRYAA NPC1 1856/4885MEN1 296/4885KMT2A 529/4885
US-11427551-B2 Triazine derivative and photosensitive composition comprising same TYR, CRY2, CRY1 NPC1 1631/4885MEN1 679/4885KMT2A 525/4885
US-20200262798-A1 NOVEL TRIAZINE DERIVATIVE AND PHOTOSENSITIVE COMPOSITION COMPRISING SAME TYR, CRY2, CRY1 NPC1 1765/4885MEN1 714/4885KMT2A 749/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.